TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma

The ten-eleven-translocation 5-methylcytosine dioxygenase (TET) family of enzymes catalyzes the conversion of 5-methylcytosine (5-mC) to 5-hydroxyme-thylcytosine (5-hmC), a modified cytosine base that facilitates gene expression. Cells respond to hypoxia by inducing a transcriptional program regulat...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Mariani, Christopher J., Vasanthakumar, Aparna, Madzo, Jozef, Yesilkanal, Ali, Bhagat, Tushar, Yu, Yiting, Bhattacharyya, Sanchari, Wenger, Roland H., Cohn, Susan L., Nanduri, Jayasri, Verma, Amit, Prabhakar, Nanduri R., Godley, Lucy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516227/
https://ncbi.nlm.nih.gov/pubmed/24835990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.04.040
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