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Alterations of 5-Hydroxymethylcytosine in Human Cancers

Prior to 2009, 5-methylcytosine (5-mC) was thought to be the only biologically significant cytosine modification in mammalian DNA. With the discovery of the TET enzymes, which convert 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC), however, intense interest has emerged in determining the...

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Detalhes bibliográficos
Main Authors: Mariani, Christopher J., Madzo, Jozef, Moen, Erika L., Yesilkanal, Ali, Godley, Lucy A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795365/
https://ncbi.nlm.nih.gov/pubmed/24202321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers5030786
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