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The role of 5-hydroxymethylcytosine in human cancer
The patterns of DNA methylation in human cancer cells are highly abnormal and often involve the acquisition of DNA hypermethylation at hundreds or thousands of CpG islands that are usually unmethylated in normal tissues. The recent discovery of 5-hydroxymethylcytosine (5hmC) as an enzymatic oxidatio...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4090033/ https://ncbi.nlm.nih.gov/pubmed/24816989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-014-1896-7 |
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