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5-hydroxymethylcytosine and its potential roles in development and cancer

Only a few years ago it was demonstrated that mammalian DNA contains oxidized forms of 5-methylcytosine (5mC). The base 5-hydroxymethylcytosine (5hmC) is the most abundant of these oxidation products and is referred to as the sixth DNA base. 5hmC is produced from 5mC in an enzymatic pathway involvin...

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Detalhes bibliográficos
Main Authors: Pfeifer, Gerd P, Kadam, Swati, Jin, Seung-Gi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645968/
https://ncbi.nlm.nih.gov/pubmed/23634848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-6-10
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