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Formation of cyclobutane pyrimidine dimers at dipyrimidines containing 5-hydroxymethylcytosine
Much of the cancer-causing effects of ultraviolet radiation from the sun have been linked to the formation of dimerized DNA bases. These dimeric DNA photoproducts include the cyclobutane pyrimidine dimers (CPDs) and the pyrimidine(6–4)pyrimidone photoproducts [(6–4)PPs). CPDs are highly mutagenic an...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3731422/ https://ncbi.nlm.nih.gov/pubmed/23677065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3pp50037c |
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