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Formation of cyclobutane pyrimidine dimers at dipyrimidines containing 5-hydroxymethylcytosine

Much of the cancer-causing effects of ultraviolet radiation from the sun have been linked to the formation of dimerized DNA bases. These dimeric DNA photoproducts include the cyclobutane pyrimidine dimers (CPDs) and the pyrimidine(6–4)pyrimidone photoproducts [(6–4)PPs). CPDs are highly mutagenic an...

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Autors principals: Kim, Sang-in, Jin, Seung-Gi, Pfeifer, Gerd P.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731422/
https://ncbi.nlm.nih.gov/pubmed/23677065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3pp50037c
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