5-hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations

The base 5-hydroxymethylcytosine (5hmC) was recently identified as an oxidation product of 5-methylcytosine (5mC) in mammalian DNA. Here, using sensitive and quantitative methods to assess levels of 5-hydroxymethyl-2′-deoxycytidine (5hmdC) and 5-methyl-2′-deoxycytidine (5mdC) in genomic DNA, we inve...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Jin, Seung-Gi, Jiang, Yong, Qiu, Runxiang, Rauch, Tibor A., Wang, Yinsheng, Schackert, Gabriele, Krex, Dietmar, Lu, Qiang, Pfeifer, Gerd P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242933/
https://ncbi.nlm.nih.gov/pubmed/22052461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2023
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller