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Concise Review: Preleukemic Stem Cells: Molecular Biology and Clinical Implications of the Precursors to Leukemia Stem Cells

Recent experimental evidence has shown that acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) arise from transformed immature hematopoietic cells following the accumulation of multiple stepwise genetic and epigenetic changes in hematopoietic stem cells and committed progenitors. The s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pandolfi, Ashley, Barreyro, Laura, Steidl, Ulrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: AlphaMed Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659760/
https://ncbi.nlm.nih.gov/pubmed/23349328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2012-0109
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