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Concise Review: Preleukemic Stem Cells: Molecular Biology and Clinical Implications of the Precursors to Leukemia Stem Cells

Recent experimental evidence has shown that acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) arise from transformed immature hematopoietic cells following the accumulation of multiple stepwise genetic and epigenetic changes in hematopoietic stem cells and committed progenitors. The s...

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Autori principali: Pandolfi, Ashley, Barreyro, Laura, Steidl, Ulrich
Natura: Artigo
Lingua:Inglês
Pubblicazione: AlphaMed Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659760/
https://ncbi.nlm.nih.gov/pubmed/23349328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2012-0109
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