Differentiation therapy for IDH1/2 mutant malignancies

le Garrett-Bakelman, Francine E, Melnick, Ari M
Foilsithe 2013

Mutant IDH: a targetable driver of leukemic phenotypes linking metabolism, epigenetics and transcriptional regulation

le Garrett-Bakelman, Francine E, Melnick, Ari M
Foilsithe in Epigenomics (2016)

COCOA: coordinate covariation analysis of epigenetic heterogeneity

le Lawson, John T., Smith, Jason P., Bekiranov, Stefan, Garrett-Bakelman, Francine E., Sheffield, Nathan C.
Foilsithe in Genome Biol (2020)

The effects of Eculizumab on the pathology of malignant atrophic papulosis

le Magro, Cynthia M, Wang, Xuan, Garrett-Bakelman, Francine, Laurence, Jeffrey, Shapiro, Lee S, DeSancho, Maria T
Foilsithe 2013

methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles

le Akalin, Altuna, Kormaksson, Matthias, Li, Sheng, Garrett-Bakelman, Francine E, Figueroa, Maria E, Melnick, Ari, Mason, Christopher E
Foilsithe 2012

Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution

le Garrett-Bakelman, Francine E., Sheridan, Caroline K., Kacmarczyk, Thadeous J., Ishii, Jennifer, Betel, Doron, Alonso, Alicia, Mason, Christopher E., Figueroa, Maria E., Melnick, Ari M.
Foilsithe in J Vis Exp (2015)

An optimized algorithm for detecting and annotating regional differential methylation

le Li, Sheng, Garrett-Bakelman, Francine E, Akalin, Altuna, Zumbo, Paul, Levine, Ross, To, Bik L, Lewis, Ian D, Brown, Anna L, D'Andrea, Richard J, Melnick, Ari, Mason, Christopher E
Foilsithe 2013

Aid is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells

le Kunimoto, Hiroyoshi, McKenney, Anna Sophia, Meydan, Cem, Shank, Kaitlyn, Nazir, Abbas, Rapaport, Franck, Durham, Benjamin, Garrett-Bakelman, Francine E., Pronier, Elodie, Shih, Alan H., Melnick, Ari, Chaudhuri, Jayanta, Levine, Ross L.
Foilsithe in Blood (2017)

Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity

le Kunimoto, Hiroyoshi, Meydan, Cem, Nazir, Abbas, Whitfield, Justin, Shank, Kaitlyn, Rapaport, Franck, Maher, Rebecca, Pronier, Elodie, Meyer, Sara C., Garrett-Bakelman, Francine E., Tallman, Martin, Melnick, Ari, Levine, Ross L., Shih, Alan H.
Foilsithe in Cancer Cell (2017)

CD97 is a critical regulator of acute myeloid leukemia stem cell function

le Martin, Gaëlle H., Roy, Nainita, Chakraborty, Sohini, Desrichard, Alexis, Chung, Stephen S., Woolthuis, Carolien M., Hu, Wenhuo, Berezniuk, Iryna, Garrett-Bakelman, Francine E., Hamann, Jörg, Devlin, Sean M., Chan, Timothy A., Park, Christopher Y.
Foilsithe in J Exp Med (2019)

Dynamic evolution of clonal epialleles revealed by methclone

le Li, Sheng, Garrett-Bakelman, Francine, Perl, Alexander E, Luger, Selina M, Zhang, Chao, To, Bik L, Lewis, Ian D, Brown, Anna L, D’Andrea, Richard J, Ross, M Elizabeth, Levine, Ross, Carroll, Martin, Melnick, Ari, Mason, Christopher E
Foilsithe in Genome Biol (2014)

Satb1 regulates hematopoietic stem cell self-renewal by promoting quiescence and repressing differentiation commitment

le Will, Britta, Vogler, Thomas O., Bartholdy, Boris, Garrett-Bakelman, Francine, Mayer, Jillian, Barreyro, Laura, Pandolfi, Ashley, Todorova, Tihomira I., Okoye-Okafor, Ujunwa C., Stanley, Robert F., Bhagat, Tushar D., Verma, Amit, Figueroa, Maria E., Melnick, Ari, Roth, Michael, Steidl, Ulrich
Foilsithe 2013

Combination targeted therapy to disrupt aberrant oncogenic signaling and reverse epigenetic dysfunction in IDH2- and TET2-mutant acute myeloid leukemia

le Shih, Alan H, Meydan, Cem, Shank, Kaitlyn, Garrett-Bakelman, Francine E, Ward, Patrick S, Intlekofer, Andrew, Nazir, Abbas, Stein, Eytan, Knapp, Kristina, Glass, Jacob, Travins, Jeremy, Straley, Kim, Gliser, Camelia, Mason, Chris, Yen, Katharine, Thompson, Craig B, Melnick, Ari, Levine, Ross L
Foilsithe in Cancer Discov (2017)

Targeted detection and quantitation of histone modifications from 1,000 cells

le Abshiru, Nebiyu A., Sikora, Jacek W., Camarillo, Jeannie M., Morris, Juliette A., Compton, Philip D., Lee, Tak, Neelamraju, Yaseswini, Haddox, Samuel, Sheridan, Caroline, Carroll, Martin, Cripe, Larry D., Tallman, Martin S., Paietta, Elisabeth M., Melnick, Ari M., Thomas, Paul M., Garrett-Bakelman, Francine E., Kelleher, Neil L.
Foilsithe in PLoS One (2020)

Chemotherapy induces senescence-like resilient cells capable of initiating AML recurrence

le Duy, Cihangir, Li, Meng, Teater, Matt, Meydan, Cem, Garrett-Bakelman, Francine E., Lee, Tak C., Chin, Christopher R., Durmaz, Ceyda, Kawabata, Kimihito C., Dhimolea, Eugen, Mitsiades, Constantine S., Doehner, Hartmut, D’Andrea, Richard J., Becker, Michael W., Paietta, Elisabeth M., Mason, Christopher E., Carroll, Martin, Melnick, Ari M.
Foilsithe in Cancer Discov (2021)

The N(6)-methyladenosine (m(6)A)-forming enzyme METTL3 controls myeloid differentiation of normal and leukemia cells

le Vu, Ly P., Pickering, Brian F., Cheng, Yuanming, Zaccara, Sara, Nguyen, Diu, Minuesa, Gerard, Chou, Timothy, Chow, Arthur, Saletore, Yogesh, MacKay, Matthew, Schulman, Jessica, Famulare, Christopher, Patel, Minal, Klimek, Virginia M., Garrett-Bakelman, Francine E., Melnick, Ari, Carroll, Martin, Mason, Christopher E., Jaffrey, Samie R., Kharas, Michael G.
Foilsithe in Nat Med (2017)

A hybrid mechanism of action for BCL6 in B-cells defined by formation of functionally distinct complexes at enhancers and promoters

le Hatzi, Katerina, Jiang, Yanwen, Huang, Chuanxin, Garrett-Bakelman, Francine, Gearhart, Micah D., Giannopoulou, Eugenia G., Zumbo, Paul, Kirouac, Kevin, Bhaskara, Srividya, Polo, Jose M., Kormaksson, Matthias, MacKerell, Alexander D., Xue, Fengtian, Mason, Christopher E., Hiebert, Scott W., Prive, Gilbert G., Cerchietti, Leandro, Bardwell, Vivian J., Elemento, Olivier, Melnick, Ari
Foilsithe 2013

Epigenetic identity in AML depends on disruption of non-promoter regulatory elements and is affected by antagonistic effects of mutations in epigenetic modifiers

le Glass, Jacob L., Hassane, Duane, Wouters, Bas J., Kunimoto, Hiroyoshi, Avellino, Roberto, Garrett-Bakelman, Francine E., Guryanova, Olga A., Bowman, Robert, Redlich, Shira, Intlekofer, Andrew M., Meydan, Cem, Qin, Tingting, Fall, Mame, Alonso, Alicia, Guzman, Monica L., Valk, Peter J.M., Thompson, Craig B., Levine, Ross, Elemento, Olivier, Delwel, Ruud, Melnick, Ari, Figueroa, Maria E.
Foilsithe in Cancer Discov (2017)

Base-Pair Resolution DNA Methylation Sequencing Reveals Profoundly Divergent Epigenetic Landscapes in Acute Myeloid Leukemia

le Akalin, Altuna, Garrett-Bakelman, Francine E., Kormaksson, Matthias, Busuttil, Jennifer, Zhang, Lu, Khrebtukova, Irina, Milne, Thomas A., Huang, Yongsheng, Biswas, Debabrata, Hess, Jay L., Allis, C. David, Roeder, Robert G., Valk, Peter J. M., Löwenberg, Bob, Delwel, Ruud, Fernandez, Hugo F., Paietta, Elisabeth, Tallman, Martin S., Schroth, Gary P., Mason, Christopher E., Melnick, Ari, Figueroa, Maria E.
Foilsithe 2012

An Esrrb and Nanog Cell Fate Regulatory Module Controlled by Feed Forward Loop Interactions

le Sevilla, Ana, Papatsenko, Dimitri, Mazloom, Amin R., Xu, Huilei, Vasileva, Ana, Unwin, Richard D., LeRoy, Gary, Chen, Edward Y., Garrett-Bakelman, Francine E., Lee, Dung-Fang, Trinite, Benjamin, Webb, Ryan L., Wang, Zichen, Su, Jie, Gingold, Julian, Melnick, Ari, Garcia, Benjamin A., Whetton, Anthony D., MacArthur, Ben D., Ma’ayan, Avi, Lemischka, Ihor R.
Foilsithe in Front Cell Dev Biol (2021)