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Dynamic evolution of clonal epialleles revealed by methclone
We describe methclone, a novel method to identify epigenetic loci that harbor large changes in the clonality of their epialleles (epigenetic alleles). Methclone efficiently analyzes genome-wide DNA methylation sequencing data. We quantify the changes using a composition entropy difference calculatio...
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| Publicat a: | Genome Biol |
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| Autors principals: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4242486/ https://ncbi.nlm.nih.gov/pubmed/25260792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0472-5 |
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