A carregar...
Differentiation therapy for IDH1/2 mutant malignancies
Recently discovered recurrent somatic mutations in the key metabolic enzymes IDH1 and IDH2 produce the aberrant oncometabolite 2-HG and contribute to malignant transformation of hematopoietic and glial cells. Two recent reports in Science describe the first IDH1 and IDH2 mutant-specific small-molecu...
Na minha lista:
| Main Authors: | , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3731561/ https://ncbi.nlm.nih.gov/pubmed/23732524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.73 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|