TET2 as an epigenetic master regulator for normal and malignant hematopoiesis

Por Nakajima, Hideaki, Kunimoto, Hiroyoshi
Publicado no Cancer Sci (2014)

Tet2 disruption leads to enhanced self-renewal and altered differentiation of fetal liver hematopoietic stem cells

Por Kunimoto, Hiroyoshi, Fukuchi, Yumi, Sakurai, Masatoshi, Sadahira, Ken, Ikeda, Yasuo, Okamoto, Shinichiro, Nakajima, Hideaki
Publicado em 2012

Aid is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells

Por Kunimoto, Hiroyoshi, McKenney, Anna Sophia, Meydan, Cem, Shank, Kaitlyn, Nazir, Abbas, Rapaport, Franck, Durham, Benjamin, Garrett-Bakelman, Francine E., Pronier, Elodie, Shih, Alan H., Melnick, Ari, Chaudhuri, Jayanta, Levine, Ross L.
Publicado no Blood (2017)

Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity

Por Kunimoto, Hiroyoshi, Meydan, Cem, Nazir, Abbas, Whitfield, Justin, Shank, Kaitlyn, Rapaport, Franck, Maher, Rebecca, Pronier, Elodie, Meyer, Sara C., Garrett-Bakelman, Francine E., Tallman, Martin, Melnick, Ari, Levine, Ross L., Shih, Alan H.
Publicado no Cancer Cell (2017)

Epigenetic identity in AML depends on disruption of non-promoter regulatory elements and is affected by antagonistic effects of mutations in epigenetic modifiers

Por Glass, Jacob L., Hassane, Duane, Wouters, Bas J., Kunimoto, Hiroyoshi, Avellino, Roberto, Garrett-Bakelman, Francine E., Guryanova, Olga A., Bowman, Robert, Redlich, Shira, Intlekofer, Andrew M., Meydan, Cem, Qin, Tingting, Fall, Mame, Alonso, Alicia, Guzman, Monica L., Valk, Peter J.M., Thompson, Craig B., Levine, Ross, Elemento, Olivier, Delwel, Ruud, Melnick, Ari, Figueroa, Maria E.
Publicado no Cancer Discov (2017)