Myelodysplastic Syndrome Progression to Acute Myeloid Leukemia at the Stem Cell Level

per Chen, Jiahao, Kao, Yun-Ruei, Sun, Daqian, Todorova, Tihomira I., Reynolds, David, Narayanagari, Swathi-Rao, Montagna, Cristina, Will, Britta, Verma, Amit, Steidl, Ulrich
Publicat a Nat Med (2018)

Direct activation of BAX by BTSA1 overcomes apoptosis resistance in acute myeloid leukemia

per Reyna, Denis E., Garner, Thomas P., Lopez, Andrea, Kopp, Felix, Choudhary, Gaurav S., Sridharan, Ashwin, Narayanagari, Swathi-Rao, Mitchell, Kelly, Dong, Baoxia, Bartholdy, Boris A., Walensky, Loren D., Verma, Amit, Steidl, Ulrich, Gavathiotis, Evripidis
Publicat a Cancer Cell (2017)

IL1RAP potentiates multiple oncogenic signaling pathways in AML

per Mitchell, Kelly, Barreyro, Laura, Todorova, Tihomira I., Taylor, Samuel J., Antony-Debré, Iléana, Narayanagari, Swathi-Rao, Carvajal, Luis A., Leite, Joana, Piperdi, Zubair, Pendurti, Gopichand, Mantzaris, Ioannis, Paietta, Elisabeth, Verma, Amit, Gritsman, Kira, Steidl, Ulrich
Publicat a J Exp Med (2018)

Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia

per Carvajal, Luis A., Neriah, Daniela Ben, Senecal, Adrien, Benard, Lumie, Thiruthuvanathan, Victor, Yatsenko, Tatyana, Narayanagari, Swathi-Rao, Wheat, Justin C., Todorova, Tihomira I., Mitchell, Kelly, Kenworthy, Charles, Guerlavais, Vincent, Annis, D. Allen, Bartholdy, Boris, Will, Britta, Anampa, Jesus D., Mantzaris, Ioannis, Aivado, Manuel, Singer, Robert H., Coleman, Robert A., Verma, Amit, Steidl, Ulrich
Publicat a Sci Transl Med (2018)

Pharmacological inhibition of the transcription factor PU.1 in leukemia

per Antony-Debré, Iléana, Paul, Ananya, Leite, Joana, Mitchell, Kelly, Kim, Hye Mi, Carvajal, Luis A., Todorova, Tihomira I., Huang, Kenneth, Kumar, Arvind, Farahat, Abdelbasset A., Bartholdy, Boris, Narayanagari, Swathi-Rao, Chen, Jiahao, Ambesi-Impiombato, Alberto, Ferrando, Adolfo A., Mantzaris, Ioannis, Gavathiotis, Evripidis, Verma, Amit, Will, Britta, Boykin, David W., Wilson, W. David, Poon, Gregory M.K., Steidl, Ulrich
Publicat a J Clin Invest (2017)

A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy

per Amgalan, Dulguun, Garner, Thomas P., Pekson, Ryan, Jia, Xiaotong F., Yanamandala, Mounica, Paulino, Victor, Liang, Felix G., Corbalan, J. Jose, Lee, Jaehoon, Chen, Yun, Karagiannis, George S., Sanchez, Luis Rivera, Liang, Huizhi, Narayanagari, Swathi-Rao, Mitchell, Kelly, Lopez, Andrea, Margulets, Victoria, Scarlata, Marco, Santulli, Gaetano, Asnani, Aarti, Peterson, Randall T., Hazan, Rachel B., Condeelis, John S., Oktay, Maja H., Steidl, Ulrich, Kirshenbaum, Lorrie A., Gavathiotis, Evripidis, Kitsis, Richard N.
Publicat a Nat Cancer (2020)

Novel IDH1 Mutant Inhibitors for Treatment of Acute Myeloid Leukemia

per Okoye-Okafor, Ujunwa C., Bartholdy, Boris, Cartier, Jessy, Gao, Enoch, Pietrak, Beth, Rendina, Alan R., Rominger, Cynthia, Quinn, Chad, Smallwood, Angela, Wiggall, Kenneth J., Reif, Alexander J., Schmidt, Stanley J., Qi, Hongwei, Zhao, Huizhen, Joberty, Gerard, Faelth-Savitski, Maria, Bantscheff, Marcus, Drewes, Gerard, Duraiswami, Chaya, Brady, Pat, Groy, Arthur, Narayanagari, Swathi-Rao, Antony-Debre, Ileana, Mitchell, Kelly, Wang, Heng Rui, Kao, Yun-Ruei, Christopeit, Maximilian, Carvajal, Luis, Barreyro, Laura, Paietta, Elisabeth, Makishima, Hideki, Will, Britta, Concha, Nestor, Adams, Nicholas D., Schwartz, Benjamin, McCabe, Michael T., Maciejewski, Jaroslav, Verma, Amit, Steidl, Ulrich
Publicat a Nat Chem Biol (2015)