Hydrogen Exchange – Mass Spectrometry Measures Stapled Peptide Conformational Dynamics and Predicts Pharmacokinetic Properties

por Shi, Xiangguo (Eric), Wales, Thomas E., Elkin, Carl, Kawahata, Noriyuki, Engen, John R., Annis, D. Allen
Publicado 2013

MDM4 inhibition: a novel therapeutic strategy to reactivate p53 in hepatoblastoma

por Woodfield, Sarah E., Shi, Yan, Patel, Roma H., Chen, Zhenghu, Shah, Aayushi P., Srivastava, Rohit K., Whitlock, Richard S., Ibarra, Aryana M., Larson, Samuel R., Sarabia, Stephen F., Badachhape, Andrew, Starosolski, Zbigniew, Ghaghada, Ketan B., Sumazin, Pavel, Annis, D. Allen, López-Terrada, Dolores, Vasudevan, Sanjeev A.
Publicado en Sci Rep (2021)

Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia

por Carvajal, Luis A., Neriah, Daniela Ben, Senecal, Adrien, Benard, Lumie, Thiruthuvanathan, Victor, Yatsenko, Tatyana, Narayanagari, Swathi-Rao, Wheat, Justin C., Todorova, Tihomira I., Mitchell, Kelly, Kenworthy, Charles, Guerlavais, Vincent, Annis, D. Allen, Bartholdy, Boris, Will, Britta, Anampa, Jesus D., Mantzaris, Ioannis, Aivado, Manuel, Singer, Robert H., Coleman, Robert A., Verma, Amit, Steidl, Ulrich
Publicado en Sci Transl Med (2018)

Stapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy

por Chang, Yong S., Graves, Bradford, Guerlavais, Vincent, Tovar, Christian, Packman, Kathryn, To, Kwong-Him, Olson, Karen A., Kesavan, Kamala, Gangurde, Pranoti, Mukherjee, Aditi, Baker, Theresa, Darlak, Krzysztof, Elkin, Carl, Filipovic, Zoran, Qureshi, Farooq Z., Cai, Hongliang, Berry, Pamela, Feyfant, Eric, Shi, Xiangguo E., Horstick, James, Annis, D. Allen, Manning, Anthony M., Fotouhi, Nader, Nash, Huw, Vassilev, Lyubomir T., Sawyer, Tomi K.
Publicado 2013

Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models

por Ng, Samuel Y., Yoshida, Noriaki, Christie, Amanda L., Ghandi, Mahmoud, Dharia, Neekesh V., Dempster, Joshua, Murakami, Mark, Shigemori, Kay, Morrow, Sara N., Van Scoyk, Alexandria, Cordero, Nicolas A., Stevenson, Kristen E., Puligandla, Maneka, Haas, Brian, Lo, Christopher, Meyers, Robin, Gao, Galen, Cherniack, Andrew, Louissaint, Abner, Nardi, Valentina, Thorner, Aaron R., Long, Henry, Qiu, Xintao, Morgan, Elizabeth A., Dorfman, David M., Fiore, Danilo, Jang, Julie, Epstein, Alan L., Dogan, Ahmet, Zhang, Yanming, Horwitz, Steven M., Jacobsen, Eric D., Santiago, Solimar, Ren, Jian-Guo, Guerlavais, Vincent, Annis, D. Allen, Aivado, Manuel, Saleh, Mansoor N., Mehta, Amitkumar, Tsherniak, Aviad, Root, David, Vazquez, Francisca, Hahn, William C., Inghirami, Giorgio, Aster, Jon C., Weinstock, David M., Koch, Raphael
Publicado en Nat Commun (2018)