Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers

Por Zhang, Xiaoyang, Choi, Peter S., Francis, Joshua M., Imielinski, Marcin, Watanabe, Hideo, Cherniack, Andrew D., Meyerson, Matthew
Publicado no Nat Genet (2015)

RPC4046, A Novel Anti-interleukin-13 Antibody, Blocks IL-13 Binding to IL-13 α1 and α2 Receptors: A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation First-in-Human Stu...

Por Tripp, Catherine S., Cuff, Carolyn, Campbell, Andrew L., Hendrickson, Barbara A., Voss, Jeff, Melim, Terry, Wu, Chengbin, Cherniack, Andrew D., Kim, Kenneth
Publicado no Adv Ther (2017)

G(α)11 Signaling through ARF6 Regulates F-Actin Mobilization and GLUT4 Glucose Transporter Translocation to the Plasma Membrane

Por Bose, Avirup, Cherniack, Andrew D., Langille, Stephen E., Nicoloro, Sarah M. C., Buxton, Joanne M., Park, Jin G., Chawla, Anil, Czech, Michael P.
Publicado em 2001

Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes

Por Powelka, Aimee M., Seth, Asha, Virbasius, Joseph V., Kiskinis, Evangelos, Nicoloro, Sarah M., Guilherme, Adilson, Tang, Xiaoqing, Straubhaar, Juerg, Cherniack, Andrew D., Parker, Malcolm G., Czech, Michael P.
Publicado em 2005

A tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

Por Bar-Peled, Liron, Chantranupong, Lynne, Cherniack, Andrew D., Chen, Walter W., Ottina, Kathleen A., Grabiner, Brian C., Spear, Eric D., Carter, Scott L., Meyerson, Matthew, Sabatini, David M.
Publicado em 2013

Glioblastoma-derived Epidermal Growth Factor Receptor (EGFR) carboxyl-terminal deletion mutants are transforming and are sensitive to EGFR-directed therapies

Por Cho, Jeonghee, Pastorino, Sandra, Zeng, Qing, Xu, Xiaoyin, Johnson, William, Vandenberg, Scott, Verhaak, Roel, Cherniack, Andrew, Watanabe, Hideo, Dutt, Amit, Kwon, Jihyun, Chao, Ying S., Onofrio, Robert C., Chiang, Derek, Yuza, Yuki, Kesari, Santosh, Meyerson, Matthew
Publicado em 2011

Genetic modifiers of EGFR dependence in non-small cell lung cancer

Por Sharifnia, Tanaz, Rusu, Victor, Piccioni, Federica, Bagul, Mukta, Imielinski, Marcin, Cherniack, Andrew D., Pedamallu, Chandra Sekhar, Wong, Bang, Wilson, Frederick H., Garraway, Levi A., Altshuler, David, Golub, Todd R., Root, David E., Subramanian, Aravind, Meyerson, Matthew
Publicado no Proc Natl Acad Sci U S A (2014)

Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

Por Holst, Frederik, Hoivik, Erling A., Gibson, William J., Taylor-Weiner, Amaro, Schumacher, Steven E., Asmann, Yan W., Grossmann, Patrick, Trovik, Jone, Necela, Brian M., Thompson, E. Aubrey, Meyerson, Matthew, Beroukhim, Rameen, Salvesen, Helga B., Cherniack, Andrew D.
Publicado no Sci Rep (2016)

Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

Por Holst, Frederik, Hoivik, Erling A., Gibson, William J., Taylor-Weiner, Amaro, Schumacher, Steven E., Asmann, Yan W., Grossmann, Patrick, Trovik, Jone, Necela, Brian M., Thompson, E. Aubrey, Meyerson, Matthew, Beroukhim, Rameen, Salvesen, Helga B., Cherniack, Andrew D.
Publicado no Sci Rep (2016)

Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

Por Holst, Frederik, Hoivik, Erling A., Gibson, William J., Taylor-Weiner, Amaro, Schumacher, Steven E., Asmann, Yan W., Grossmann, Patrick, Trovik, Jone, Necela, Brian M., Thompson, E. Aubrey, Meyerson, Matthew, Beroukhim, Rameen, Salvesen, Helga B., Cherniack, Andrew D.
Publicado no Sci Rep (2017)

Pan-cancer patterns of somatic copy-number alteration

Por Zack, Travis I., Schumacher, Steven E., Carter, Scott L., Cherniack, Andrew D., Saksena, Gordon, Tabak, Barbara, Lawrence, Michael S., Zhang, Cheng-Zhong, Wala, Jeremiah, Mermel, Craig H., Sougnez, Carrie, Gabriel, Stacey B., Hernandez, Bryan, Shen, Hui, Laird, Peter W., Getz, Gad, Meyerson, Matthew, Beroukhim, Rameen
Publicado em 2013

Integrated Molecular Characterization of Uterine Carcinosarcoma

Por Cherniack, Andrew, Shen, Hui, Walter, Vonn, Stewart, Chip, Murray, Bradley, Bowlby, Reanne, Hu, Xin, Ling, Shiyun, Soslow, Robert A., Broaddus, Russell R., Zuna, Rosemary E., Robertson, Gordon, Laird, Peter W., Kucherlapati, Raju, Mills, Gordon B, Weinstein, John N, Zhang, Jiashan, Akbani, Rehan, Levine, Douglas A
Publicado no Cancer Cell (2017)

GENO-06 A PAN-GLIOMA CHARACTERIZATION OF GENOMIC, EPIGENOMIC AND TRANSCRIPTOMIC ACTIVITIES REVEALS NOVEL RELATIONSHIPS BETWEEN HISTOLOGICAL SUBTYPES AND MOLECULAR SIGNATURES

Por Barthel, Floris P., Ceccarelli, Michele, Malta, Tathiane M., Sabedot, Thais S., Salama, Sofie R., Pagnotta, Stefano M., Murray, Bradley A., Morozova, Olena, Newton, Yulia, Brat, Daniel J., Cherniack, Andrew D., Zhang, Hailei, Poisson, Laila, Cooper, Lee, Rabadan, Raul, Laird, Peter W., Gutmann, David H., Noushmehr, Houtan, Iavarone, Antonio, Verhaak, Roel G.W.
Publicado no Neuro Oncol (2015)

The genomic landscape of tuberous sclerosis complex

Por Martin, Katie R., Zhou, Wanding, Bowman, Megan J., Shih, Juliann, Au, Kit Sing, Dittenhafer-Reed, Kristin E., Sisson, Kellie A., Koeman, Julie, Weisenberger, Daniel J., Cottingham, Sandra L., DeRoos, Steven T., Devinsky, Orrin, Winn, Mary E., Cherniack, Andrew D., Shen, Hui, Northrup, Hope, Krueger, Darcy A., MacKeigan, Jeffrey P.
Publicado no Nat Commun (2017)

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients

Por Berg, Anna, Hoivik, Erling A., Mjøs, Siv, Holst, Frederik, Werner, Henrica M. J., Tangen, Ingvild L., Taylor-Weiner, Amaro, Gibson, William J., Kusonmano, Kanthida, Wik, Elisabeth, Trovik, Jone, Halle, Mari K., Øyan, Anne M., Kalland, Karl-Henning, Cherniack, Andrew D., Beroukhim, Rameen, Stefansson, Ingunn, Mills, Gordon B., Krakstad, Camilla, Salvesen, Helga B.
Publicado no Oncotarget (2014)

Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas

Por Huo, Dezheng, Hu, Hai, Rhie, Suhn K., Gamazon, Eric R., Cherniack, Andrew D., Liu, Jianfang, Yoshimatsu, Toshio F., Pitt, Jason J., Hoadley, Katherine A., Troester, Melissa, Ru, Yuanbin, Lichtenberg, Tara, Sturtz, Lori A., Shelley, Carl S., Benz, Christopher C., Mills, Gordon B., Laird, Peter W., Shriver, Craig D., Perou, Charles M., Olopade, Olufunmilayo I.
Publicado no JAMA Oncol (2017)

DNA defects, epigenetics, and gene expression in cancer-adjacent breast: a study from The Cancer Genome Atlas

Por Troester, Melissa A, Hoadley, Katherine A, D’Arcy, Monica, Cherniack, Andrew D, Stewart, Chip, Koboldt, Daniel C, Robertson, A Gordon, Mahurkar, Swapna, Shen, Hui, Wilkerson, Matthew D, Sandhu, Rupninder, Johnson, Nicole B, Allison, Kimberly H, Beck, Andrew H, Yau, Christina, Bowen, Jay, Sheth, Margi, Hwang, E Shelley, Perou, Charles M, Laird, Peter W, Ding, Li, Benz, Christopher C
Publicado no NPJ Breast Cancer (2016)

Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

Por Lin, Wenchu, Cao, Jian, Liu, Jiayun, Beshiri, Michael L., Fujiwara, Yuko, Francis, Joshua, Cherniack, Andrew D., Geisen, Christoph, Blair, Lauren P., Zou, Mike R., Shen, Xiaohua, Kawamori, Dan, Liu, Zongzhi, Grisanzio, Chiara, Watanabe, Hideo, Minamishima, Yoji Andrew, Zhang, Qing, Kulkarni, Rohit N., Signoretti, Sabina, Rodig, Scott J., Bronson, Roderick T., Orkin, Stuart H., Tuck, David P., Benevolenskaya, Elizaveta V., Meyerson, Matthew, Kaelin, William G., Yan, Qin
Publicado em 2011

The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis

Por Gibson, William J., Hoivik, Erling A., Halle, Mari K., Taylor-Weiner, Amaro, Cherniack, Andrew D., Berg, Anna, Holst, Frederik, Zack, Travis I., Werner, Henrica M. J., Staby, Kjersti M., Rosenberg, Mara, Stefansson, Ingunn M., Kusonmano, Kanthida, Chevalier, Aaron, Mauland, Karen K., Trovik, Jone, Krakstad, Camilla, Giannakis, Marios, Hodis, Eran, Woie, Kathrine, Bjorge, Line, Vintermyr, Olav K., Wala, Jeremiah A., Lawrence, Michael S., Getz, Gad, Carter, Scott L., Beroukhim, Rameen, Salvesen, Helga B.
Publicado no Nat Genet (2016)

Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors

Por Akbay, Esra A, Koyama, Shohei, Carretero, Julian, Altabef, Abigail, Tchaicha, Jeremy H, Christensen, Camilla L, Mikse, Oliver R, Cherniack, Andrew D, Beauchamp, Ellen M, Pugh, Trevor J, Wilkerson, Matthew D, Fecci, Peter E, Butaney, Mohit, Reibel, Jacob B, Soucheray, Margaret, Cohoon, Travis J, Janne, Pasi A, Meyerson, Matthew, Hayes, D. Neil, Shapiro, Geoffrey I, Shimamura, Takeshi, Sholl, Lynette M, Rodig, Scott J, Freeman, Gordon J, Hammerman, Peter S, Dranoff, Glenn, Wong, Kwok-Kin
Publicado em 2013