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Genomic and Functional Approaches to Understanding Cancer Aneuploidy

Aneuploidy, whole chromosome or chromosome arm imbalance, is a near-universal characteristic of human cancers. In 10,522 cancer genomes from The Cancer Genome Atlas (TCGA), aneuploidy was correlated with TP53 mutation, somatic mutation rate, and expression of proliferation genes. Aneuploidy was anti...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Cell
Prif Awduron: Taylor, Alison M., Shih, Juliann, Ha, Gavin, Gao, Galen F., Zhang, Xiaoyang, Berger, Ashton C., Schumacher, Steven E., Wang, Chen, Hu, Hai, Liu, Jianfang, Lazar, Alexander J., Cherniack, Andrew D., Beroukhim, Rameen, Meyerson, Matthew
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028190/
https://ncbi.nlm.nih.gov/pubmed/29622463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.03.007
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