Genomic and Functional Approaches to Understanding Cancer Aneuploidy

Aneuploidy, whole chromosome or chromosome arm imbalance, is a near-universal characteristic of human cancers. In 10,522 cancer genomes from The Cancer Genome Atlas (TCGA), aneuploidy was correlated with TP53 mutation, somatic mutation rate, and expression of proliferation genes. Aneuploidy was anti...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Taylor, Alison M., Shih, Juliann, Ha, Gavin, Gao, Galen F., Zhang, Xiaoyang, Berger, Ashton C., Schumacher, Steven E., Wang, Chen, Hu, Hai, Liu, Jianfang, Lazar, Alexander J., Cherniack, Andrew D., Beroukhim, Rameen, Meyerson, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028190/
https://ncbi.nlm.nih.gov/pubmed/29622463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.03.007
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