Genomic and Functional Approaches to Understanding Cancer Aneuploidy

Aneuploidy, whole chromosome or chromosome arm imbalance, is a near-universal characteristic of human cancers. In 10,522 cancer genomes from The Cancer Genome Atlas (TCGA), aneuploidy was correlated with TP53 mutation, somatic mutation rate, and expression of proliferation genes. Aneuploidy was anti...

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Опубликовано в: :Cancer Cell
Главные авторы: Taylor, Alison M., Shih, Juliann, Ha, Gavin, Gao, Galen F., Zhang, Xiaoyang, Berger, Ashton C., Schumacher, Steven E., Wang, Chen, Hu, Hai, Liu, Jianfang, Lazar, Alexander J., Cherniack, Andrew D., Beroukhim, Rameen, Meyerson, Matthew
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028190/
https://ncbi.nlm.nih.gov/pubmed/29622463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.03.007
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