Ancestry-specific predisposing germline variants in cancer

BACKGROUND: Distinct prevalence of inherited genetic predisposition may partially explain the difference of cancer risks across ancestries. Ancestry-specific analyses of germline genomes are required to inform cancer genetic risk and prognosis of diverse populations. METHODS: We conducted analyses u...

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Détails bibliographiques
Publié dans:Genome Med
Auteurs principaux: Oak, Ninad, Cherniack, Andrew D., Mashl, R. Jay, Hirsch, Fred R., Ding, Li, Beroukhim, Rameen, Gümüş, Zeynep H., Plon, Sharon E., Huang, Kuan-lin
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260738/
https://ncbi.nlm.nih.gov/pubmed/32471518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00744-3
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