The role of the Mre11–Rad50–Nbs1 complex in double-strand break repair—facts and myths

Por Takeda, Shunichi, Hoa, Nguyen Ngoc, Sasanuma, Hiroyuki
Publicado no J Radiat Res (2016)

Remodeling of the Rad51 DNA Strand-Exchange Protein by the Srs2 Helicase

Por Sasanuma, Hiroyuki, Furihata, Yuko, Shinohara, Miki, Shinohara, Akira
Publicado em 2013

Targeted induction of meiotic double-strand breaks reveals chromosomal domain-dependent regulation of Spo11 and interactions among potential sites of meiotic recombination

Por Fukuda, Tomoyuki, Kugou, Kazuto, Sasanuma, Hiroyuki, Shibata, Takehiko, Ohta, Kunihiro
Publicado em 2008

Meiotic association between Spo11 regulated by Rec102, Rec104 and Rec114

Por Sasanuma, Hiroyuki, Murakami, Hajime, Fukuda, Tomoyuki, Shibata, Takehiko, Nicolas, Alain, Ohta, Kunihiro
Publicado em 2007

Impact of DNA repair pathways on the cytotoxicity of piperlongumine in chicken DT40 cell-lines

Por Okamoto, Saki, Narita, Takeo, Sasanuma, Hiroyuki, Takeda, Shunichi, Masunaga, Shin-ichiro, Bessho, Tadayoshi, Tano, Keizo
Publicado em 2014

The Double-Strand Break Landscape of Meiotic Chromosomes Is Shaped by the Paf1 Transcription Elongation Complex in Saccharomyces cerevisiae

Por Gothwal, Santosh K., Patel, Neem J., Colletti, Meaghan M., Sasanuma, Hiroyuki, Shinohara, Miki, Hochwagen, Andreas, Shinohara, Akira
Publicado no Genetics (2016)

Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells

Por Hashimoto, Kiyohiro, Sharma, Vyom, Sasanuma, Hiroyuki, Tian, Xu, Takata, Minoru, Takeda, Shunichi, Swenberg, James A., Nakamura, Jun
Publicado no Oncotarget (2016)

Cdc7-dependent phosphorylation of Mer2 facilitates initiation of yeast meiotic recombination

Por Sasanuma, Hiroyuki, Hirota, Kouji, Fukuda, Tomoyuki, Kakusho, Naoko, Kugou, Kazuto, Kawasaki, Yasuo, Shibata, Takehiko, Masai, Hisao, Ohta, Kunihiro
Publicado em 2008

Smarcal1 promotes double-strand-break repair by nonhomologous end-joining

Por Keka, Islam Shamima, Mohiuddin, Maede, Yuko, Rahman, Md Maminur, Sakuma, Tetsushi, Honma, Masamitsu, Yamamoto, Takashi, Takeda, Shunichi, Sasanuma, Hiroyuki
Publicado no Nucleic Acids Res (2015)

BRCA1 and CtIP Are Both Required to Recruit Dna2 at Double-Strand Breaks in Homologous Recombination

Por Hoa, Nguyen Ngoc, Kobayashi, Junya, Omura, Masato, Hirakawa, Mayumi, Yang, Soo-Hyun, Komatsu, Kenshi, Paull, Tanya T., Takeda, Shunichi, Sasanuma, Hiroyuki
Publicado no PLoS One (2015)

Interference in DNA Replication Can Cause Mitotic Chromosomal Breakage Unassociated with Double-Strand Breaks

Por Fujita, Mari, Sasanuma, Hiroyuki, Yamamoto, Kimiyo N., Harada, Hiroshi, Kurosawa, Aya, Adachi, Noritaka, Omura, Masato, Hiraoka, Masahiro, Takeda, Shunichi, Hirota, Kouji
Publicado em 2013

A new protein complex promoting the assembly of Rad51 filaments

Por Sasanuma, Hiroyuki, Tawaramoto, Maki S., Lao, Jessica P., Hosaka, Harumi, Sanda, Eri, Suzuki, Mamoru, Yamashita, Eiki, Hunter, Neil, Shinohara, Miki, Nakagawa, Atsushi, Shinohara, Akira
Publicado no Nat Commun (2013)

Rec8 Guides Canonical Spo11 Distribution along Yeast Meiotic Chromosomes

Por Kugou, Kazuto, Fukuda, Tomoyuki, Yamada, Shintaro, Ito, Masaru, Sasanuma, Hiroyuki, Mori, Saori, Katou, Yuki, Itoh, Takehiko, Matsumoto, Kouji, Shibata, Takehiko, Shirahige, Katsuhiko, Ohta, Kunihiro
Publicado em 2009

The role of HERC2 and RNF8 ubiquitin E3 ligases in the promotion of translesion DNA synthesis in the chicken DT40 cell line

Por Mohiuddin, Kobayashi, Shunsuke, Keka, Islam Shamima, Guilbaud, Guillaume, Sale, Julian, Narita, Takeo, Abdel-Aziz, H. Ismail, Wang, Xin, Ogawa, Saki, Sasanuma, Hiroyuki, Chiu, Roland, Oestergaard, Vibe H., Lisby, Michael, Takeda, Shunichi
Publicado no DNA Repair (Amst) (2016)

Abacavir, an anti–HIV-1 drug, targets TDP1-deficient adult T cell leukemia

Por Tada, Kohei, Kobayashi, Masayuki, Takiuchi, Yoko, Iwai, Fumie, Sakamoto, Takashi, Nagata, Kayoko, Shinohara, Masanobu, Io, Katsuhiro, Shirakawa, Kotaro, Hishizawa, Masakatsu, Shindo, Keisuke, Kadowaki, Norimitsu, Hirota, Kouji, Yamamoto, Junpei, Iwai, Shigenori, Sasanuma, Hiroyuki, Takeda, Shunichi, Takaori-Kondo, Akifumi
Publicado no Sci Adv (2015)