Impact of DNA repair pathways on the cytotoxicity of piperlongumine in chicken DT40 cell-lines

Piperlongumine is a naturally-occurring small molecule with various biological activities. Recent studies demonstrate that piperlongumine selectively kills various types of transformed cells with minimal toxicity to non-transformed cells by inducing a high level of reactive oxygen species (ROS). ROS...

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Detalhes bibliográficos
Main Authors: Okamoto, Saki, Narita, Takeo, Sasanuma, Hiroyuki, Takeda, Shunichi, Masunaga, Shin-ichiro, Bessho, Tadayoshi, Tano, Keizo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162141/
https://ncbi.nlm.nih.gov/pubmed/25221646
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