Participation of TDP1 in the repair of formaldehyde-induced DNA-protein cross-links in chicken DT40 cells

Proteins are covalently trapped on DNA to form DNA-protein cross-links (DPCs) when cells are exposed to DNA-damaging agents. Aldehyde compounds produce common types of DPCs that contain proteins in an undisrupted DNA strand. Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs topoisomerase 1 (TOPO1) that...

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Publicado en:PLoS One
Main Authors: Nakano, Toshiaki, Shoulkamy, Mahmoud I., Tsuda, Masataka, Sasanuma, Hiroyuki, Hirota, Kouji, Takata, Minoru, Masunaga, Shin-ichiro, Takeda, Shunichi, Ide, Hiroshi, Bessho, Tadayoshi, Tano, Keizo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7319324/
https://ncbi.nlm.nih.gov/pubmed/32589683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234859
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