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Selective cytotoxicity of the anti-diabetic drug, metformin, in glucose-deprived chicken DT40 cells
Metformin is a biguanide drug that is widely used in the treatment of diabetes. Epidemiological studies have indicated that metformin exhibits anti-cancer activity. However, the molecular mechanisms underlying this activity currently remain unclear. We hypothesized that metformin is cytotoxic in a t...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5605006/ https://ncbi.nlm.nih.gov/pubmed/28926637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185141 |
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