Interplay between DNA polymerases ß and λ in repair of oxidation DNA damage in chicken DT40 cells

DNA polymerase λ (Pol λ) is a DNA polymerase β (Pol β)-like enzyme with both DNA synthetic and 5'-deoxyribose-5'-phosphate lyase domains. Resent biochemical studies implicated Pol λ as a backup enzyme to Pol ß in the mammalian base excision repair (BER) pathway. To examine the interrelatio...

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Bibliographic Details
Main Authors: Tano, Keizo, Nakamura, Jun, Asagoshi, Kenjiro, Arakawa, Hiroshi, Sonoda, Eiichiro, Braithwaite, Elena K., Prasad, Rajendra, Buerstedde, Jean-Marie, Takeda, Shunichi, Watanabe, Masami, Wilson, Samuel H.
Format: Artigo
Language:Inglês
Published: 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080795/
https://ncbi.nlm.nih.gov/pubmed/17363341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.01.011
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