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The role of the Mre11–Rad50–Nbs1 complex in double-strand break repair—facts and myths
Homologous recombination (HR) initiates double-strand break (DSB) repair by digesting 5′-termini at DSBs, the biochemical reaction called DSB resection, during which DSBs are processed by nucleases to generate 3′ single-strand DNA. Rad51 recombinase polymerizes along resected DNA, and the resulting...
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| Publicado no: | J Radiat Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4990115/ https://ncbi.nlm.nih.gov/pubmed/27311583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrw034 |
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