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Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers
Whole genome analysis approaches are revealing recurrent cancer-associated somatic alterations in non-coding DNA regions. We combined somatic copy number analysis of 12 tumor types with tissue-specific epigenetic profiling to identify significant regions of focal amplification harboring super-enhanc...
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| Pubblicato in: | Nat Genet |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4857881/ https://ncbi.nlm.nih.gov/pubmed/26656844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3470 |
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