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Insertions and deletions target lineage-defining genes in human cancers
Whole genome sequencing analysis of lung adenocarcinomas revealed noncoding somatic mutational hotspots near VMP1/MIR21 and indel hotspots in surfactant protein genes (SFTPA1, SFTPB, and SFTPC). Extrapolation to other solid cancers demonstrated highly recurrent and tumor-type-specific indel hotspots...
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| Publicado no: | Cell |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5564321/ https://ncbi.nlm.nih.gov/pubmed/28089356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.12.025 |
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