Genomic rearrangements by LINE-1 insertion-mediated deletion in the human and chimpanzee lineages

Long INterspersed Elements (LINE-1s or L1s) are abundant non-LTR retrotransposons in mammalian genomes that are capable of insertional mutagenesis. They have been associated with target site deletions upon insertion in cell culture studies of retrotransposition. Here, we report 50 deletion events in...

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Main Authors: Han, Kyudong, Sen, Shurjo K., Wang, Jianxin, Callinan, Pauline A., Lee, Jungnam, Cordaux, Richard, Liang, Ping, Batzer, Mark A.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1179734/
https://ncbi.nlm.nih.gov/pubmed/16034026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki718
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