Small Molecule Inhibitors of Zinc-dependent Histone Deacetylases

מאת Wagner, Florence F., Weїwer, Michel, Lewis, Michael C., Holson, Edward B.
יצא לאור 2013

Characterization of plant-derived saponin natural products against Candida albicans

מאת Coleman, Jeffrey J., Okoli, Ikechukwu, Tegos, George P., Holson, Edward B., Wagner, Florence F., Hamblin, Michael R., Mylonakis, Eleftherios
יצא לאור 2010

Isoform-selective inhibitor of histone deacetylase 3 (HDAC3) limits pancreatic islet infiltration and protects female nonobese diabetic mice from diabetes

מאת Dirice, Ercument, Ng, Raymond W. S., Martinez, Rachael, Hu, Jiang, Wagner, Florence F., Holson, Edward B., Wagner, Bridget K., Kulkarni, Rohit N.
הוצא לאור ב J Biol Chem (2017)

Signal-dependent repression of DUSP5 by class I HDACs controls nuclear ERK activity and cardiomyocyte hypertrophy

מאת Ferguson, Bradley S., Harrison, Brooke C., Jeong, Mark Y., Reid, Brian G., Wempe, Michael F., Wagner, Florence F., Holson, Edward B., McKinsey, Timothy A.
יצא לאור 2013

Selective HDAC Inhibition for the Disruption of Latent HIV-1 Infection

מאת Barton, Kirston M., Archin, Nancie M., Keedy, Kara S., Espeseth, Amy S., Zhang, Yan-ling, Gale, Jennifer, Wagner, Florence F., Holson, Edward B., Margolis, David M.
יצא לאור 2014

Hydroxamate-based Histone Deacetylase Inhibitors Can Protect Neurons from Oxidative Stress via an HDAC-independent Catalase-like Mechanism

מאת Olson, David E., Sleiman, Sama F., Bourassa, Megan W., Wagner, Florence F., Gale, Jennifer P., Zhang, Yan-Ling, Ratan, Rajiv R., Holson, Edward B.
הוצא לאור ב Chem Biol (2015)

Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis

מאת Chou, Danny Hung-Chieh, Holson, Edward B., Wagner, Florence F., Tang, Alicia J., Maglathlin, Rebecca L., Lewis, Timothy A., Schreiber, Stuart L., Wagner, Bridget K.
יצא לאור 2012

Class I HDAC imaging using [(3)H]CI-994 autoradiography

מאת Wang, Yajie, Zhang, Yan-Ling, Hennig, Krista, Gale, Jennifer P., Hong, Yijia, Cha, Anna, Riley, Misha, Wagner, Florence, Haggarty, Stephen J., Holson, Edward, Hooker, Jacob
יצא לאור 2013

The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in ovarian cancer cells

מאת Wilson, Andrew J, Holson, Edward, Wagner, Florence, Zhang, Yan-Ling, Fass, Daniel M, Haggarty, Stephen J, Bhaskara, Srividya, Hiebert, Scott W, Schreiber, Stuart L, Khabele, Dineo
יצא לאור 2011

Activity of caffeic acid phenethyl ester in Caenorhabditis elegans

מאת Coleman, Jeffrey J, Komura, Tomomi, Munro, Julia, Wu, Michael P, Busanelli, Rakhee R, Koehler, Angela N, Thomas, Méryl, Wagner, Florence F, Holson, Edward B, Mylonakis, Eleftherios
הוצא לאור ב Future Med Chem (2016)

Enhancer of Zeste Homolog 2 (EZH2) Mediates Glucolipotoxicity-Induced Apoptosis in β-Cells

מאת Dahlby, Tina, Simon, Christian, Backe, Marie Balslev, Dahllöf, Mattias Salling, Holson, Edward, Wagner, Bridget K., Böni-Schnetzler, Marianne, Marzec, Michal Tomasz, Lundh, Morten, Mandrup-Poulsen, Thomas
הוצא לאור ב Int J Mol Sci (2020)

In Vivo Imaging of Histone Deacetylases (HDACs) in the Central Nervous System and Major Peripheral Organs

מאת Wang, Changning, Schroeder, Frederick A., Wey, Hsiao-Ying, Borra, Ronald, Wagner, Florence F., Reis, Surya, Kim, Sung Won, Holson, Edward B., Haggarty, Stephen J., Hooker, Jacob M.
יצא לאור 2014

Identification of Antifungal Compounds Active against Candida albicans Using an Improved High-Throughput Caenorhabditis elegans Assay

מאת Okoli, Ikechukwu, Coleman, Jeffrey J., Tempakakis, Emmanouil, An, W. Frank, Holson, Edward, Wagner, Florence, Conery, Annie L., Larkins-Ford, Jonah, Wu, Gang, Stern, Andy, Ausubel, Frederick M., Mylonakis, Eleftherios
יצא לאור 2009

Correction: Identification of Antifungal Compounds Active against Candida albicans Using an Improved High-Throughput Caenorhabditis elegans Assay

מאת Okoli, Ikechukwu, Coleman, Jeffrey J., Tampakakis, Emmanouil, An, W. Frank, Holson, Edward, Wagner, Florence, Conery, Annie L., Larkins-Ford, Jonah, Wu, Gang, Stern, Andy, Ausubel, Frederick M., Mylonakis, Eleftherios
יצא לאור 2010

Design, synthesis, and evaluation of hydroxamic acid-based molecular probes for in vivo imaging of histone deacetylase (HDAC) in brain

מאת Wang, Changning, Eessalu, Thomas E, Barth, Vanessa N, Mitch, Charles H, Wagner, Florence F, Hong, Yijia, Neelamegam, Ramesh, Schroeder, Frederick A, Holson, Edward B, Haggarty, Stephen J, Hooker, Jacob M
יצא לאור 2013

Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Can Mediate Neuroprotection Independent of HDAC Inhibition

מאת Sleiman, Sama F., Olson, David E., Bourassa, Megan W., Karuppagounder, Saravanan S., Zhang, Yan-Ling, Gale, Jennifer, Wagner, Florence F., Basso, Manuela, Coppola, Giovanni, Pinto, John T., Holson, Edward B., Ratan, Rajiv R.
יצא לאור 2014

Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate

מאת Sleiman, Sama F, Henry, Jeffrey, Al-Haddad, Rami, El Hayek, Lauretta, Abou Haidar, Edwina, Stringer, Thomas, Ulja, Devyani, Karuppagounder, Saravanan S, Holson, Edward B, Ratan, Rajiv R, Ninan, Ipe, Chao, Moses V
הוצא לאור ב eLife (2016)

Lactate is an antidepressant that mediates resilience to stress by modulating the hippocampal levels and activity of histone deacetylases

מאת Karnib, Nabil, El-Ghandour, Rim, El Hayek, Lauretta, Nasrallah, Patrick, Khalifeh, Mohamad, Barmo, Nour, Jabre, Vanessa, Ibrahim, Pascale, Bilen, Maria, Stephan, Joseph S., Holson, Edward B., Ratan, Rajiv R., Sleiman, Sama F.
הוצא לאור ב Neuropsychopharmacology (2019)

EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression

מאת Renneville, Aline, Van Galen, Peter, Canver, Matthew C., McConkey, Marie, Krill-Burger, John M., Dorfman, David M., Holson, Edward B., Bernstein, Bradley E., Orkin, Stuart H., Bauer, Daniel E., Ebert, Benjamin L.
הוצא לאור ב Blood (2015)

Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts

מאת Schuetze, Katherine B., Stratton, Matthew S., Blakeslee, Weston W., Wempe, Michael F., Wagner, Florence F., Holson, Edward B., Kuo, Yin-Ming, Andrews, Andrew J., Gilbert, Tonya M., Hooker, Jacob M., McKinsey, Timothy A.
הוצא לאור ב J Pharmacol Exp Ther (2017)