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Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Can Mediate Neuroprotection Independent of HDAC Inhibition
Histone deacetylase (HDAC) inhibition improves function and extends survival in rodent models of a host of neurological conditions, including stroke, and neurodegenerative diseases. Our understanding, however, of the contribution of individual HDAC isoforms to neuronal death is limited. In this stud...
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Huvudupphovsmän: | , , , , , , , , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
Society for Neuroscience
2014
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4205555/ https://ncbi.nlm.nih.gov/pubmed/25339746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1010-14.2014 |
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