Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Can Mediate Neuroprotection Independent of HDAC Inhibition

Histone deacetylase (HDAC) inhibition improves function and extends survival in rodent models of a host of neurological conditions, including stroke, and neurodegenerative diseases. Our understanding, however, of the contribution of individual HDAC isoforms to neuronal death is limited. In this stud...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Sleiman, Sama F., Olson, David E., Bourassa, Megan W., Karuppagounder, Saravanan S., Zhang, Yan-Ling, Gale, Jennifer, Wagner, Florence F., Basso, Manuela, Coppola, Giovanni, Pinto, John T., Holson, Edward B., Ratan, Rajiv R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Society for Neuroscience 2014
विषय:
Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205555/
https://ncbi.nlm.nih.gov/pubmed/25339746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1010-14.2014
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