Class I HDAC imaging using [(3)H]CI-994 autoradiography

[(3)H]CI-994, a radioactive isotopologue of the benzamide CI-994, a class I histone deacetylase inhibitor (HDACi), was evaluated as an autoradiography probe for ex vivo labeling and localizing of class I HDAC (isoforms 1–3) in the rodent brain. After protocol optimization, up to 80% of total binding...

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Detalhes bibliográficos
Main Authors: Wang, Yajie, Zhang, Yan-Ling, Hennig, Krista, Gale, Jennifer P., Hong, Yijia, Cha, Anna, Riley, Misha, Wagner, Florence, Haggarty, Stephen J., Holson, Edward, Hooker, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781195/
https://ncbi.nlm.nih.gov/pubmed/23803584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.25202
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