HDAC6 Brain Mapping with [(18)F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination

[Image: see text] Histone deacetylase 6 (HDAC6) function and dysregulation have been implicated in the etiology of certain cancers and more recently in central nervous system (CNS) disorders including Rett syndrome, Alzheimer’s and Parkinson’s diseases, and major depressive disorder. HDAC6-selective...

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Detalhes bibliográficos
Publicado no:ACS Cent Sci
Main Authors: Strebl, Martin G., Campbell, Arthur J., Zhao, Wen-Ning, Schroeder, Frederick A., Riley, Misha M., Chindavong, Peter S., Morin, Thomas M., Haggarty, Stephen J., Wagner, Florence F., Ritter, Tobias, Hooker, Jacob M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620987/
https://ncbi.nlm.nih.gov/pubmed/28979942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.7b00274
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