In Vivo Imaging of Histone Deacetylases (HDACs) in the Central Nervous System and Major Peripheral Organs

[Image: see text] Epigenetic enzymes are now targeted to treat the underlying gene expression dysregulation that contribute to disease pathogenesis. Histone deacetylases (HDACs) have shown broad potential in treatments against cancer and emerging data supports their targeting in the context of cardi...

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Detalhes bibliográficos
Main Authors: Wang, Changning, Schroeder, Frederick A., Wey, Hsiao-Ying, Borra, Ronald, Wagner, Florence F., Reis, Surya, Kim, Sung Won, Holson, Edward B., Haggarty, Stephen J., Hooker, Jacob M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191584/
https://ncbi.nlm.nih.gov/pubmed/25203558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500872p
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