Studies toward the Total Synthesis of Dihydrolycolucine. Preparation of AB and CEF Ring Fragments

Por Cash, Brandon M., Prevost, Natacha, Wagner, Florence F., Comins, Daniel L.
Publicado em 2014

Small Molecule Inhibitors of Zinc-dependent Histone Deacetylases

Por Wagner, Florence F., Weїwer, Michel, Lewis, Michael C., Holson, Edward B.
Publicado em 2013

Characterization of plant-derived saponin natural products against Candida albicans

Por Coleman, Jeffrey J., Okoli, Ikechukwu, Tegos, George P., Holson, Edward B., Wagner, Florence F., Hamblin, Michael R., Mylonakis, Eleftherios
Publicado em 2010

Signal-dependent repression of DUSP5 by class I HDACs controls nuclear ERK activity and cardiomyocyte hypertrophy

Por Ferguson, Bradley S., Harrison, Brooke C., Jeong, Mark Y., Reid, Brian G., Wempe, Michael F., Wagner, Florence F., Holson, Edward B., McKinsey, Timothy A.
Publicado em 2013

Selective HDAC Inhibition for the Disruption of Latent HIV-1 Infection

Por Barton, Kirston M., Archin, Nancie M., Keedy, Kara S., Espeseth, Amy S., Zhang, Yan-ling, Gale, Jennifer, Wagner, Florence F., Holson, Edward B., Margolis, David M.
Publicado em 2014

Hydroxamate-based Histone Deacetylase Inhibitors Can Protect Neurons from Oxidative Stress via an HDAC-independent Catalase-like Mechanism

Por Olson, David E., Sleiman, Sama F., Bourassa, Megan W., Wagner, Florence F., Gale, Jennifer P., Zhang, Yan-Ling, Ratan, Rajiv R., Holson, Edward B.
Publicado no Chem Biol (2015)

Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis

Por Chou, Danny Hung-Chieh, Holson, Edward B., Wagner, Florence F., Tang, Alicia J., Maglathlin, Rebecca L., Lewis, Timothy A., Schreiber, Stuart L., Wagner, Bridget K.
Publicado em 2012

Class I HDAC imaging using [(3)H]CI-994 autoradiography

Por Wang, Yajie, Zhang, Yan-Ling, Hennig, Krista, Gale, Jennifer P., Hong, Yijia, Cha, Anna, Riley, Misha, Wagner, Florence, Haggarty, Stephen J., Holson, Edward, Hooker, Jacob
Publicado em 2013

The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in ovarian cancer cells

Por Wilson, Andrew J, Holson, Edward, Wagner, Florence, Zhang, Yan-Ling, Fass, Daniel M, Haggarty, Stephen J, Bhaskara, Srividya, Hiebert, Scott W, Schreiber, Stuart L, Khabele, Dineo
Publicado em 2011

In Vivo Imaging of Histone Deacetylases (HDACs) in the Central Nervous System and Major Peripheral Organs

Por Wang, Changning, Schroeder, Frederick A., Wey, Hsiao-Ying, Borra, Ronald, Wagner, Florence F., Reis, Surya, Kim, Sung Won, Holson, Edward B., Haggarty, Stephen J., Hooker, Jacob M.
Publicado em 2014

Identification of Antifungal Compounds Active against Candida albicans Using an Improved High-Throughput Caenorhabditis elegans Assay

Por Okoli, Ikechukwu, Coleman, Jeffrey J., Tempakakis, Emmanouil, An, W. Frank, Holson, Edward, Wagner, Florence, Conery, Annie L., Larkins-Ford, Jonah, Wu, Gang, Stern, Andy, Ausubel, Frederick M., Mylonakis, Eleftherios
Publicado em 2009

Correction: Identification of Antifungal Compounds Active against Candida albicans Using an Improved High-Throughput Caenorhabditis elegans Assay

Por Okoli, Ikechukwu, Coleman, Jeffrey J., Tampakakis, Emmanouil, An, W. Frank, Holson, Edward, Wagner, Florence, Conery, Annie L., Larkins-Ford, Jonah, Wu, Gang, Stern, Andy, Ausubel, Frederick M., Mylonakis, Eleftherios
Publicado em 2010

Design, synthesis, and evaluation of hydroxamic acid-based molecular probes for in vivo imaging of histone deacetylase (HDAC) in brain

Por Wang, Changning, Eessalu, Thomas E, Barth, Vanessa N, Mitch, Charles H, Wagner, Florence F, Hong, Yijia, Neelamegam, Ramesh, Schroeder, Frederick A, Holson, Edward B, Haggarty, Stephen J, Hooker, Jacob M
Publicado em 2013

Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Can Mediate Neuroprotection Independent of HDAC Inhibition

Por Sleiman, Sama F., Olson, David E., Bourassa, Megan W., Karuppagounder, Saravanan S., Zhang, Yan-Ling, Gale, Jennifer, Wagner, Florence F., Basso, Manuela, Coppola, Giovanni, Pinto, John T., Holson, Edward B., Ratan, Rajiv R.
Publicado em 2014

Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts

Por Schuetze, Katherine B., Stratton, Matthew S., Blakeslee, Weston W., Wempe, Michael F., Wagner, Florence F., Holson, Edward B., Kuo, Yin-Ming, Andrews, Andrew J., Gilbert, Tonya M., Hooker, Jacob M., McKinsey, Timothy A.
Publicado no J Pharmacol Exp Ther (2017)

FDG-PET imaging reveals local brain glucose utilization is altered by class I histone deacetylase inhibitors

Por Schroeder, Frederick A., Chonde, Daniel B., Riley, Misha M., Moseley, Christian K., Granda, Michael L., Wilson, Colin M., Wagner, Florence F., Zhang, Yan-Ling, Gale, Jennifer, Holson, Edward B., Haggarty, Stephen J., Hooker, Jacob M.
Publicado em 2013

Image-Guided Synthesis Reveals Potent Blood-Brain Barrier Permeable Histone Deacetylase Inhibitors

Por Seo, Young Jun, Kang, Yeona, Muench, Lisa, Reid, Alicia, Caesar, Shannon, Jean, Logan, Wagner, Florence, Holson, Edward, Haggarty, Stephen J., Weiss, Philipp, King, Payton, Carter, Pauline, Volkow, Nora D., Fowler, Joanna S., Hooker, Jacob M., Kim, Sung Won
Publicado em 2014

Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells

Por Kubicek, Stefan, Gilbert, Joshua C., Fomina-Yadlin, Dina, Gitlin, Alexander D., Yuan, Yuan, Wagner, Florence F., Holson, Edward B., Luo, Tuoping, Lewis, Timothy A., Taylor, Bradley, Gupta, Supriya, Shamji, Alykhan F., Wagner, Bridget K., Clemons, Paul A., Schreiber, Stuart L.
Publicado em 2012

Epigenetic Priming of Memory Updating during Reconsolidation to Attenuate Remote Fear Memories

Por Gräff, Johannes, Joseph, Nadine F., Horn, Meryl E., Samiei, Alireza, Meng, Jia, Seo, Jinsoo, Rei, Damien, Bero, Adam W., Phan, Trongha X., Wagner, Florence, Holson, Edward, Xu, Jinbin, Sun, Jianjun, Neve, Rachael L., Mach, Robert H., Haggarty, Stephen J., Tsai, Li-Huei
Publicado em 2014

AKT Kinase Activity Is Required for Lithium to Modulate Mood-Related Behaviors in Mice

Por Pan, Jen Q, Lewis, Michael C, Ketterman, Josh K, Clore, Elizabeth L, Riley, Misha, Richards, Keenan R, Berry-Scott, Erin, Liu, Xiulin, Wagner, Florence F, Holson, Edward B, Neve, Rachael L, Biechele, Travis L, Moon, Randall T, Scolnick, Edward M, Petryshen, Tracey L, Haggarty, Stephen J
Publicado em 2011