Tonic Dopamine Inhibition of L-Type Ca(2+) Channel Activity Reduces α(1D) Ca(2+) Channel Gene Expression

Por Fass, Daniel M., Takimoto, Koichi, Mains, Richard E., Levitan, Edwin S.
Publicado no J Neurosci (1999)

Epigenetic Mechanisms in Mood Disorders: Targeting Neuroplasticity

Por Fass, Daniel M., Schroeder, Frederick A., Perlis, Roy H., Haggarty, Stephen J.
Publicado em 2013

Highly Expandable Human iPS Cell-Derived Neural Progenitor Cells (NPC) and Neurons for Central Nervous System Disease Modeling and High-Throughput Screening

Por Cheng, Chialin, Fass, Daniel M., Folz-Donahue, Kat, MacDonald, Marcy E., Haggarty, Stephen J.
Publicado no Curr Protoc Hum Genet (2017)

Kinetic Tuning of HDAC Inhibitors Affords Potent Inducers of Progranulin Expression

Por Moreno-Yruela, Carlos, Fass, Daniel M., Cheng, Chialin, Herz, Joachim, Olsen, Christian A., Haggarty, Stephen J.
Publicado no ACS Chem Neurosci (2019)

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

Por Kilgore, Mark, Miller, Courtney A, Fass, Daniel M, Hennig, Krista M, Haggarty, Stephen J, Sweatt, J David, Rumbaugh, Gavin
Publicado em 2010

Regulation of Primitive Hematopoiesis by Class I Histone Deacetylases

Por Shah, Rishita R., Koniski, Anne, Shinde, Mansi, Blythe, Shelby A., Fass, Daniel M., Haggarty, Stephen J., Palis, James, Klein, Peter S.
Publicado em 2013

Dissecting Structure-Activity-Relationships of Crebinostat: Brain Penetrant HDAC Inhibitors for Neuroepigenetic Regulation

Por Ghosh, Balaram, Zhao, Wen-Ning, Reis, Surya A., Patnaik, Debasis, Fass, Daniel M., Tsai, Li-Huei, Mazitschek, Ralph, Haggarty, Stephen J.
Publicado no Bioorg Med Chem Lett (2016)

Recruitment of CREB Binding Protein Is Sufficient for CREB-Mediated Gene Activation

Por Cardinaux, Jean-Rene, Notis, John C., Zhang, Qinghong, Vo, Ngan, Craig, Johanna C., Fass, Daniel M., Brennan, Richard G., Goodman, Richard H.
Publicado em 2000

The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in ovarian cancer cells

Por Wilson, Andrew J, Holson, Edward, Wagner, Florence, Zhang, Yan-Ling, Fass, Daniel M, Haggarty, Stephen J, Bhaskara, Srividya, Hiebert, Scott W, Schreiber, Stuart L, Khabele, Dineo
Publicado em 2011

Automated structure–activity relationship mining: connecting chemical structure to biological profiles

Por Wawer, Mathias J., Jaramillo, David E., Dancik, Vlado, Fass, Daniel M., Haggarty, Stephen J., Shamji, Alykhan F., Wagner, Bridget K., Schreiber, Stuart L., Clemons, Paul A.
Publicado no J Biomol Screen (2014)

Short-Chain HDAC Inhibitors Differentially Affect Vertebrate Development and Neuronal Chromatin

Por Fass, Daniel M., Shah, Rishita, Ghosh, Balaram, Hennig, Krista, Norton, Stephanie, Zhao, Wen-Ning, Reis, Surya A., Klein, Peter S., Mazitschek, Ralph, Maglathlin, Rebecca L., Lewis, Timothy A., Haggarty, Stephen J.
Publicado em 2010

Dysregulation of miR-34a Links Neuronal Development to Genetic Risk Factors for Bipolar Disorder

Por Bavamian, Sabine, Mellios, Nikolaos, Lalonde, Jasmin, Fass, Daniel M., Wang, Jennifer, Sheridan, Steven D., Madison, Jon M., Zhou, Fen, Rueckert, Erroll H., Barker, Doug, Perlis, Roy H., Sur, Mriganka, Haggarty, Stephen J.
Publicado no Mol Psychiatry (2015)

WNT/β-Catenin Pathway and Epigenetic Mechanisms Regulate the Pitt-Hopkins Syndrome and Schizophrenia Risk Gene TCF4

Por Hennig, Krista M., Fass, Daniel M., Zhao, Wen-Ning, Sheridan, Steven D., Fu, Ting, Erdin, Serkan, Stortchevoi, Alexei, Lucente, Diane, Cody, Jannine D., Sweetser, David, Gusella, James F., Talkowski, Michael E., Haggarty, Stephen J.
Publicado no Mol Neuropsychiatry (2017)

Chemical-Genetic Screen Identifies Riluzole as an Enhancer of Wnt/β-catenin signaling in Melanoma

Por Biechele, Travis L., Camp, Nathan D., Fass, Daniel M., Kulikauskas, Rima M., Robin, Nick C., White, Bryan D., Taraska, Corinne M., Moore, Erin C., Muster, Jeanot, Karmacharya, Rakesh, Haggarty, Stephen J., Chien, Andy J., Moon, Randall T.
Publicado em 2010

Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice

Por Kovalenko, Marina, Erdin, Serkan, Andrew, Marissa A, St Claire, Jason, Shaughnessey, Melissa, Hubert, Leroy, Neto, João Luís, Stortchevoi, Alexei, Fass, Daniel M, Mouro Pinto, Ricardo, Haggarty, Stephen J, Wilson, John H, Talkowski, Michael E, Wheeler, Vanessa C
Publicado no eLife (2020)

Functional Analysis of Rare Variants Found in Schizophrenia Implicates a Critical Role for GIT1-PAK3 Signaling in Neuroplasticity

Por Kim, Myung Jong, Biag, Jonathan, Fass, Daniel M., Lewis, Michael C., Zhang, Qiangge, Fleishman, Morgan, Gangwar, Shanti Pal, Machius, Mischa, Fromer, Menachem, Purcell, Shaun M., McCarroll, Steven A., Rudenko, Gabby, Premont, Richard T., Scolnick, Edward M., Haggarty, Stephen J.
Publicado no Mol Psychiatry (2016)

Bruton’s Tyrosine Kinase Revealed as a Negative Regulator of Wnt–β-Catenin Signaling

Por James, Richard G., Biechele, Travis L., Conrad, William H., Camp, Nathan D., Fass, Daniel M., Major, Michael B., Sommer, Karen, Yi, XianHua, Roberts, Brian S., Cleary, Michele A., Arthur, William T., MacCoss, Michael, Rawlings, David J., Haggarty, Stephen J., Moon, Randall T.
Publicado no Sci Signal (2009)

An epigenetic blockade of cognitive functions in the neurodegenerating brain

Por Gräff, Johannes, Rei, Damien, Guan, Ji-Song, Wang, Wen-Yuan, Seo, Jinsoo, Hennig, Krista M., Nieland, Thomas J.F., Fass, Daniel M., Kao, Patricia F., Kahn, Martin, Su, Susan C., Samiei, Alireza, Joseph, Nadine, Haggarty, Stephen J., Delalle, Ivana, Tsai, Li-Huei
Publicado em 2012

Crebinostat: A Novel Cognitive Enhancer that Inhibits Histone Deacetylase Activity and Modulates Chromatin-Mediated Neuroplasticity

Por Fass, Daniel M., Reis, Surya A., Ghosh, Balaram, Hennig, Krista M., Joseph, Nadine F., Zhao, Wen-Ning, Nieland, Thomas J.F., Guan, Ji-Song, Kuhnle, Chelsea E. Groves, Tang, Weiping, Barker, Douglas D., Mazitschek, Ralph, Schreiber, Stuart L., Tsai, Li-Huei, Haggarty, Stephen J.
Publicado em 2012

A Selective HDAC 1/2 Inhibitor Modulates Chromatin and Gene Expression in Brain and Alters Mouse Behavior in Two Mood-Related Tests

Por Schroeder, Frederick A., Lewis, Michael C., Fass, Daniel M., Wagner, Florence F., Zhang, Yan-Ling, Hennig, Krista M., Gale, Jennifer, Zhao, Wen-Ning, Reis, Surya, Barker, Douglas D., Berry-Scott, Erin, Kim, Sung Won, Clore, Elizabeth L., Hooker, Jacob M., Holson, Edward B., Haggarty, Stephen J., Petryshen, Tracey L.
Publicado em 2013