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Kinetic Tuning of HDAC Inhibitors Affords Potent Inducers of Progranulin Expression
Histone deacetylases (HDACs) are enzymes involved in the epigenetic control of gene expression. A handful of HDAC inhibitors have been approved for the treatment of cancer, and HDAC inhibition has also been proposed as a novel therapeutic strategy for neurodegenerative disorders. These disorders inc...
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| Publicado no: | ACS Chem Neurosci |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6982123/ https://ncbi.nlm.nih.gov/pubmed/31330099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.9b00281 |
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