Bruton’s Tyrosine Kinase Revealed as a Negative Regulator of Wnt–β-Catenin Signaling

Wnts are secreted ligands that activate several receptor-mediated signal transduction cascades. Homeostatic Wnt signaling through β-catenin is required in adults, because either elevation or attenuation of β-catenin function has been linked to diverse diseases. To contribute to the identification of...

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Publicado no:Sci Signal
Main Authors: James, Richard G., Biechele, Travis L., Conrad, William H., Camp, Nathan D., Fass, Daniel M., Major, Michael B., Sommer, Karen, Yi, XianHua, Roberts, Brian S., Cleary, Michele A., Arthur, William T., MacCoss, Michael, Rawlings, David J., Haggarty, Stephen J., Moon, Randall T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4790753/
https://ncbi.nlm.nih.gov/pubmed/19471023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000230
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