Bili Inhibits Wnt/β-Catenin Signaling by Regulating the Recruitment of Axin to LRP6

BACKGROUND: Insights into how the Frizzled/LRP6 receptor complex receives, transduces and terminates Wnt signals will enhance our understanding of the control of the Wnt/ß-catenin pathway. METHODOLOGY/PRINCIPAL FINDINGS: In pursuit of such insights, we performed a genome-wide RNAi screen in Drosophi...

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Main Authors: Kategaya, Lorna S., Changkakoty, Binita, Biechele, Travis, Conrad, William H., Kaykas, Ajamete, DasGupta, Ramanuj, Moon, Randall T.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701632/
https://ncbi.nlm.nih.gov/pubmed/19572019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006129
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