Wnt-induced dephosphorylation of Axin releases β-catenin from the Axin complex

The stabilization of β-catenin is a key regulatory step during cell fate changes and transformations to tumor cells. Several interacting proteins, including Axin, APC, and the protein kinase GSK-3β are implicated in regulating β-catenin phosphorylation and its subsequent degradation. Wnt signaling s...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Willert, Karl, Shibamoto, Sayumi, Nusse, Roel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 1999
Assuntos:	Research Communication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316878/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10421629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.14.1768
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