Small Molecule Inhibitors of Zinc-dependent Histone Deacetylases

Lysine acetylation is an ancient, evolutionarily conserved, reversible post-translational modification. A multitude of diverse cellular functions are regulated by this dynamic modification, including energy and metabolism, protein folding, transcription, and translation. Gene expression can be manip...

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Main Authors: Wagner, Florence F., Weїwer, Michel, Lewis, Michael C., Holson, Edward B.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2013
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805861/
https://ncbi.nlm.nih.gov/pubmed/24101253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-013-0226-1
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