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Profiling technologies for the identification and characterization of small-molecule histone deacetylase inhibitors
Histone deacetylases (HDACs) are promising drug targets for treating cancer, neurologic, inflammatory and metabolic diseases. Four small molecule inhibitors of HDACs have gained regulatory approval for treating lymphomas and multiple myelomas. Highly sensitive in vitro and cell-based profiling techn...
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| Publicado no: | Drug Discov Today Technol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4698312/ https://ncbi.nlm.nih.gov/pubmed/26723889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddtec.2015.10.006 |
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