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Small molecule inhibitors of histone acetyltransferases and deacetylases are potential drugs for inflammatory diseases

Lysine acetylation is a reversible post-translational modification (PTM) of cellular proteins and represents an important regulatory switch in signal transduction. Lysine acetylation, in combination with other PTMs, directs the outcomes as well as the activation levels of important signal transducti...

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Bibliografske podrobnosti
izdano v:Drug Discov Today
Main Authors: Dekker, Frank J., van den Bosch, Thea, Martin, Nathaniel I.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218544/
https://ncbi.nlm.nih.gov/pubmed/21477662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2011.03.009
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