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Small molecule inhibitors of histone acetyltransferases and deacetylases are potential drugs for inflammatory diseases

Lysine acetylation is a reversible post-translational modification (PTM) of cellular proteins and represents an important regulatory switch in signal transduction. Lysine acetylation, in combination with other PTMs, directs the outcomes as well as the activation levels of important signal transducti...

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Detalhes bibliográficos
Publicado no:Drug Discov Today
Main Authors: Dekker, Frank J., van den Bosch, Thea, Martin, Nathaniel I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218544/
https://ncbi.nlm.nih.gov/pubmed/21477662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2011.03.009
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