Identification of Antifungal Compounds Active against Candida albicans Using an Improved High-Throughput Caenorhabditis elegans Assay

Candida albicans, the most common human pathogenic fungus, can establish a persistent lethal infection in the intestine of the microscopic nematode Caenorhabditis elegans. The C. elegans–C. albicans infection model was previously adapted to screen for antifungal compounds. Modifications to this scre...

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Detalhes bibliográficos
Main Authors: Okoli, Ikechukwu, Coleman, Jeffrey J., Tempakakis, Emmanouil, An, W. Frank, Holson, Edward, Wagner, Florence, Conery, Annie L., Larkins-Ford, Jonah, Wu, Gang, Stern, Andy, Ausubel, Frederick M., Mylonakis, Eleftherios
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737148/
https://ncbi.nlm.nih.gov/pubmed/19750012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007025
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