Insect-Derived Cecropins Display Activity against Acinetobacter baumannii in a Whole-Animal High-Throughput Caenorhabditis elegans Model

The rise of multidrug-resistant Acinetobacter baumannii and a concomitant decrease in antibiotic treatment options warrants a search for new classes of antibacterial agents. We have found that A. baumannii is pathogenic and lethal to the model host organism Caenorhabditis elegans and have exploited...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Jayamani, Elamparithi, Rajamuthiah, Rajmohan, Larkins-Ford, Jonah, Fuchs, Beth Burgwyn, Conery, Annie L., Vilcinskas, Andreas, Ausubel, Frederick M., Mylonakis, Eleftherios
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
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Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325797/
https://ncbi.nlm.nih.gov/pubmed/25583713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04198-14
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