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High-throughput screening for novel anti-infectives using a C. elegans pathogenesis model

In recent history, the nematode Caenorhabditis elegans has provided a compelling platform for the discovery of novel antimicrobial drugs. In this protocol, we present an automated, high-throughput C. elegans pathogenesis assay, which can be used to screen for anti-infective compounds that prevent ne...

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Autors principals: Conery, Annie L., Larkins-Ford, Jonah, Ausubel, Frederick M., Kirienko, Natalia V.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021578/
https://ncbi.nlm.nih.gov/pubmed/24652621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470559277.ch130160
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