Threading an elephant through the eye of a needle: Where are platelets made?

gan Johnston, Ian, Hayes, Vincent, Poncz, Mortimer
Cyhoeddwyd yn Cell Res (2017)

Enhancing functional platelet release in vivo from in vitro–grown megakaryocytes using small molecule inhibitors

gan Jarocha, Danuta, Vo, Karen K., Lyde, Randolph B., Hayes, Vincent, Camire, Rodney M., Poncz, Mortimer
Cyhoeddwyd yn Blood Adv (2018)

The disulfide isomerase ERp57 is required for fibrin deposition in vivo

gan Zhou, Junsong, Wu, Yi, Wang, Lu, Rauova, Lubica, Hayes, Vincent M., Poncz, Mortimer, Essex, David W.
Cyhoeddwyd yn J Thromb Haemost (2014)

The C-terminal CGHC motif of protein disulfide isomerase supports thrombosis

gan Zhou, Junsong, Wu, Yi, Wang, Lu, Rauova, Lubica, Hayes, Vincent M., Poncz, Mortimer, Essex, David W.
Cyhoeddwyd yn J Clin Invest (2015)

Endothelial antigen assembly leads to thrombotic complications in heparin-induced thrombocytopenia

gan Hayes, Vincent, Johnston, Ian, Arepally, Gowthami M., McKenzie, Steven E., Cines, Douglas B., Rauova, Lubica, Poncz, Mortimer
Cyhoeddwyd yn J Clin Invest (2017)

Monocyte-bound PF4 in the pathogenesis of heparin-induced thrombocytopenia

gan Rauova, Lubica, Hirsch, Jessica D., Greene, Teshell K., Zhai, Li, Hayes, Vincent M., Kowalska, M. Anna, Cines, Douglas B., Poncz, Mortimer
Cyhoeddwyd 2010

Loss of ATE1-mediated arginylation leads to impaired platelet myosin phosphorylation, clot retraction, and in vivo thrombosis formation

gan Lian, Lurong, Suzuki, Aae, Hayes, Vincent, Saha, Sougata, Han, Xuemei, Xu, Tao, Yates, John R, Poncz, Mortimer, Kashina, Anna, Abrams, Charles S.
Cyhoeddwyd 2014

FLI1 level during megakaryopoiesis affects thrombopoiesis and platelet biology

gan Vo, Karen K., Jarocha, Danuta J., Lyde, Randolph B., Hayes, Vincent, Thom, Christopher S., Sullivan, Spencer K., French, Deborah L., Poncz, Mortimer
Cyhoeddwyd yn Blood (2017)

Identifying and enriching platelet-producing human stem cell–derived megakaryocytes using factor V uptake

gan Sim, Xiuli, Jarocha, Danuta, Hayes, Vincent, Hanby, Hayley A., Marks, Michael S., Camire, Rodney M., French, Deborah L., Poncz, Mortimer, Gadue, Paul
Cyhoeddwyd yn Blood (2017)

Dynamic intercellular redistribution of HIT antigen modulates heparin-induced thrombocytopenia

gan Dai, Jing, Madeeva, Daria, Hayes, Vincent, Ahn, Hyun Sook, Tutwiler, Valerie, Arepally, Gowthami M., Cines, Douglas B., Poncz, Mortimer, Rauova, Lubica
Cyhoeddwyd yn Blood (2018)

Clot contraction: compression of erythrocytes into tightly packed polyhedra and redistribution of platelets and fibrin

gan Cines, Douglas B., Lebedeva, Tatiana, Nagaswami, Chandrasekaran, Hayes, Vincent, Massefski, Walter, Litvinov, Rustem I., Rauova, Lubica, Lowery, Thomas J., Weisel, John W.
Cyhoeddwyd 2014

Pleiotropic platelet defects in mice with disrupted FOG1-NuRD interaction

gan Wang, Yuhuan, Meng, Ronghua, Hayes, Vincent, Fuentes, Rudy, Yu, Xiang, Abrams, Charles S., Heijnen, Harry F. G., Blobel, Gerd A., Marks, Michael S., Poncz, Mortimer
Cyhoeddwyd 2011

The disulfide isomerase ERp72 supports arterial thrombosis in mice

gan Zhou, Junsong, Wu, Yi, Chen, Fengwu, Wang, Lu, Rauova, Lubica, Hayes, Vincent M., Poncz, Mortimer, Li, Hong, Liu, Tong, Liu, Junling, Essex, David W.
Cyhoeddwyd yn Blood (2017)

Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo

gan Zhi, Huiying, Rauova, Lubica, Hayes, Vincent, Gao, Cunji, Boylan, Brian, Newman, Debra K., McKenzie, Steven E., Cooley, Brian C., Poncz, Mortimer, Newman, Peter J.
Cyhoeddwyd 2013

Atomic description of the immune complex involved in heparin-induced thrombocytopenia

gan Cai, Zheng, Yarovoi, Serge V., Zhu, Zhiqiang, Rauova, Lubica, Hayes, Vincent, Lebedeva, Tatiana, Liu, Qun, Poncz, Mortimer, Arepally, Gowthami, Cines, Douglas B., Greene, Mark I.
Cyhoeddwyd yn Nat Commun (2015)

Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia

gan Tutwiler, Valerie, Madeeva, Daria, Ahn, Hyun Sook, Andrianova, Izabella, Hayes, Vincent, Zheng, X. Long, Cines, Douglas B., McKenzie, Steven E., Poncz, Mortimer, Rauova, Lubica
Cyhoeddwyd yn Blood (2016)

Recognition of PF4-VWF complexes by heparin-induced thrombocytopenia antibodies contributes to thrombus propagation

gan Johnston, Ian, Sarkar, Amrita, Hayes, Vincent, Koma, Gavin T., Arepally, Gowthami M., Chen, Junmei, Chung, Dominic W., López, José A., Cines, Douglas B., Rauova, Lubica, Poncz, Mortimer
Cyhoeddwyd yn Blood (2020)

Antibodies associated with heparin-induced thrombocytopenia (HIT) inhibit activated protein C generation: new insights into the prothrombotic nature of HIT

gan Kowalska, M. Anna, Krishnaswamy, Sriram, Rauova, Lubica, Zhai, Li, Hayes, Vincent, Amirikian, Karine, Esko, Jeffrey D., Bougie, Daniel W., Aster, Richard H., Cines, Douglas B., Poncz, Mortimer
Cyhoeddwyd 2011

Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasis

gan Adair, Brian D., Alonso, José L., van Agthoven, Johannes, Hayes, Vincent, Ahn, Hyun Sook, Yu, I-Shing, Lin, Shu-Wha, Xiong, Jian-Ping, Poncz, Mortimer, Arnaout, M. Amin
Cyhoeddwyd yn Nat Commun (2020)

ADAMTS13 Autoantibodies Cloned from Patients with Acquired Thrombotic Thrombocytopenic Purpura: 2. Pathogenicity in an animal model

gan Ostertag, Eric M., Bdeir, Khalil, Kacir, Stephen, Thiboutot, Michelle, Gulendran, Gayathri, Yunk, Lenka, Hayes, Vincent M., Motto, David G., Poncz, Mortimer, Zheng, X. Long, Cines, Douglas B., Siegel, Don L.
Cyhoeddwyd yn Transfusion (2016)