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Enhancing functional platelet release in vivo from in vitro–grown megakaryocytes using small molecule inhibitors

In vitro–grown megakaryocytes for generating platelets may have value in meeting the increasing demand for platelet transfusions. Remaining challenges have included the poor yield and quality of in vitro–generated platelets. We have shown that infusing megakaryocytes leads to intrapulmonary release...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Jarocha, Danuta, Vo, Karen K., Lyde, Randolph B., Hayes, Vincent, Camire, Rodney M., Poncz, Mortimer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873227/
https://ncbi.nlm.nih.gov/pubmed/29545255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017010975
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