Threading an elephant through the eye of a needle: Where are platelets made?

Por Johnston, Ian, Hayes, Vincent, Poncz, Mortimer
Publicado no Cell Res (2017)

Enhancing functional platelet release in vivo from in vitro–grown megakaryocytes using small molecule inhibitors

Por Jarocha, Danuta, Vo, Karen K., Lyde, Randolph B., Hayes, Vincent, Camire, Rodney M., Poncz, Mortimer
Publicado no Blood Adv (2018)

The disulfide isomerase ERp57 is required for fibrin deposition in vivo

Por Zhou, Junsong, Wu, Yi, Wang, Lu, Rauova, Lubica, Hayes, Vincent M., Poncz, Mortimer, Essex, David W.
Publicado no J Thromb Haemost (2014)

The C-terminal CGHC motif of protein disulfide isomerase supports thrombosis

Por Zhou, Junsong, Wu, Yi, Wang, Lu, Rauova, Lubica, Hayes, Vincent M., Poncz, Mortimer, Essex, David W.
Publicado no J Clin Invest (2015)

Endothelial antigen assembly leads to thrombotic complications in heparin-induced thrombocytopenia

Por Hayes, Vincent, Johnston, Ian, Arepally, Gowthami M., McKenzie, Steven E., Cines, Douglas B., Rauova, Lubica, Poncz, Mortimer
Publicado no J Clin Invest (2017)

Monocyte-bound PF4 in the pathogenesis of heparin-induced thrombocytopenia

Por Rauova, Lubica, Hirsch, Jessica D., Greene, Teshell K., Zhai, Li, Hayes, Vincent M., Kowalska, M. Anna, Cines, Douglas B., Poncz, Mortimer
Publicado em 2010

Loss of ATE1-mediated arginylation leads to impaired platelet myosin phosphorylation, clot retraction, and in vivo thrombosis formation

Por Lian, Lurong, Suzuki, Aae, Hayes, Vincent, Saha, Sougata, Han, Xuemei, Xu, Tao, Yates, John R, Poncz, Mortimer, Kashina, Anna, Abrams, Charles S.
Publicado em 2014

FLI1 level during megakaryopoiesis affects thrombopoiesis and platelet biology

Por Vo, Karen K., Jarocha, Danuta J., Lyde, Randolph B., Hayes, Vincent, Thom, Christopher S., Sullivan, Spencer K., French, Deborah L., Poncz, Mortimer
Publicado no Blood (2017)

Identifying and enriching platelet-producing human stem cell–derived megakaryocytes using factor V uptake

Por Sim, Xiuli, Jarocha, Danuta, Hayes, Vincent, Hanby, Hayley A., Marks, Michael S., Camire, Rodney M., French, Deborah L., Poncz, Mortimer, Gadue, Paul
Publicado no Blood (2017)

Dynamic intercellular redistribution of HIT antigen modulates heparin-induced thrombocytopenia

Por Dai, Jing, Madeeva, Daria, Hayes, Vincent, Ahn, Hyun Sook, Tutwiler, Valerie, Arepally, Gowthami M., Cines, Douglas B., Poncz, Mortimer, Rauova, Lubica
Publicado no Blood (2018)

Clot contraction: compression of erythrocytes into tightly packed polyhedra and redistribution of platelets and fibrin

Por Cines, Douglas B., Lebedeva, Tatiana, Nagaswami, Chandrasekaran, Hayes, Vincent, Massefski, Walter, Litvinov, Rustem I., Rauova, Lubica, Lowery, Thomas J., Weisel, John W.
Publicado em 2014

Pleiotropic platelet defects in mice with disrupted FOG1-NuRD interaction

Por Wang, Yuhuan, Meng, Ronghua, Hayes, Vincent, Fuentes, Rudy, Yu, Xiang, Abrams, Charles S., Heijnen, Harry F. G., Blobel, Gerd A., Marks, Michael S., Poncz, Mortimer
Publicado em 2011

The disulfide isomerase ERp72 supports arterial thrombosis in mice

Por Zhou, Junsong, Wu, Yi, Chen, Fengwu, Wang, Lu, Rauova, Lubica, Hayes, Vincent M., Poncz, Mortimer, Li, Hong, Liu, Tong, Liu, Junling, Essex, David W.
Publicado no Blood (2017)

Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo

Por Zhi, Huiying, Rauova, Lubica, Hayes, Vincent, Gao, Cunji, Boylan, Brian, Newman, Debra K., McKenzie, Steven E., Cooley, Brian C., Poncz, Mortimer, Newman, Peter J.
Publicado em 2013

Atomic description of the immune complex involved in heparin-induced thrombocytopenia

Por Cai, Zheng, Yarovoi, Serge V., Zhu, Zhiqiang, Rauova, Lubica, Hayes, Vincent, Lebedeva, Tatiana, Liu, Qun, Poncz, Mortimer, Arepally, Gowthami, Cines, Douglas B., Greene, Mark I.
Publicado no Nat Commun (2015)

Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia

Por Tutwiler, Valerie, Madeeva, Daria, Ahn, Hyun Sook, Andrianova, Izabella, Hayes, Vincent, Zheng, X. Long, Cines, Douglas B., McKenzie, Steven E., Poncz, Mortimer, Rauova, Lubica
Publicado no Blood (2016)

Recognition of PF4-VWF complexes by heparin-induced thrombocytopenia antibodies contributes to thrombus propagation

Por Johnston, Ian, Sarkar, Amrita, Hayes, Vincent, Koma, Gavin T., Arepally, Gowthami M., Chen, Junmei, Chung, Dominic W., López, José A., Cines, Douglas B., Rauova, Lubica, Poncz, Mortimer
Publicado no Blood (2020)

Antibodies associated with heparin-induced thrombocytopenia (HIT) inhibit activated protein C generation: new insights into the prothrombotic nature of HIT

Por Kowalska, M. Anna, Krishnaswamy, Sriram, Rauova, Lubica, Zhai, Li, Hayes, Vincent, Amirikian, Karine, Esko, Jeffrey D., Bougie, Daniel W., Aster, Richard H., Cines, Douglas B., Poncz, Mortimer
Publicado em 2011

Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasis

Por Adair, Brian D., Alonso, José L., van Agthoven, Johannes, Hayes, Vincent, Ahn, Hyun Sook, Yu, I-Shing, Lin, Shu-Wha, Xiong, Jian-Ping, Poncz, Mortimer, Arnaout, M. Amin
Publicado no Nat Commun (2020)

ADAMTS13 Autoantibodies Cloned from Patients with Acquired Thrombotic Thrombocytopenic Purpura: 2. Pathogenicity in an animal model

Por Ostertag, Eric M., Bdeir, Khalil, Kacir, Stephen, Thiboutot, Michelle, Gulendran, Gayathri, Yunk, Lenka, Hayes, Vincent M., Motto, David G., Poncz, Mortimer, Zheng, X. Long, Cines, Douglas B., Siegel, Don L.
Publicado no Transfusion (2016)