Hemostatic agents of broad applicability produced by selective tuning of factor Xa zymogenicity

nork Ivanciu, Lacramioara, Camire, Rodney M.
Argitaratua izan da Blood (2015)

Insights into vitamin K-dependent carboxylation: home field advantage

nork Ayombil, Francis, Camire, Rodney M.
Argitaratua izan da Haematologica (2020)

Profile of efraloctocog alfa and its potential in the treatment of hemophilia A

nork George, Lindsey A, Camire, Rodney M
Argitaratua izan da J Blood Med (2015)

Rendering Factor Xa Zymogen-like as a Therapeutic Strategy to Treat Bleeding

nork Thalji, Nabil K., Camire, Rodney M.
Argitaratua izan da Curr Opin Hematol (2017)

The Conformational Switch from the Factor X Zymogen to Protease State Mediates Exosite Expression and Prothrombinase Assembly

nork Toso, Raffaella, Zhu, Hua, Camire, Rodney M.
Argitaratua 2008

Procoagulant Adaptation of a Blood Coagulation Prothrombinase-like Enzyme Complex in Australian Elapid Venom

nork Bos, Mettine H.A., Camire, Rodney M.
Argitaratua 2010

Blood coagulation factors V and VIII: Molecular Mechanisms of Procofactor Activation

nork Bos, Mettine H.A., Camire, Rodney M.
Argitaratua 2010

Imaging coagulation reactions in vivo

nork Ivanciu, Lacramioara, Krishnaswamy, Sriram, Camire, Rodney M.
Argitaratua 2012

A Bipartite Autoinhibitory Region within the B-domain Suppresses Function in Factor V

nork Bos, Mettine H. A., Camire, Rodney M.
Argitaratua 2012

New insights into the spatiotemporal localization of prothrombinase in vivo

nork Ivanciu, Lacramioara, Krishnaswamy, Sriram, Camire, Rodney M.
Argitaratua 2014

Zymogen-like factor Xa variants restore thrombin generation and effectively bypass the intrinsic pathway in vitro

nork Bunce, Matthew W., Toso, Raffaella, Camire, Rodney M.
Argitaratua 2011

Regulation of factor V and factor V-short by TFPIα: Relationship between B-domain proteolysis and binding

nork Petrillo, Teodolinda, Ayombil, Francis, van’t Veer, Cornelis, Camire, Rodney M.
Argitaratua izan da J Biol Chem (2021)

Restricted Active Site Docking by Enzyme-bound Substrate Enforces the Ordered Cleavage of Prothrombin by Prothrombinase

nork Hacisalihoglu, Ayse, Panizzi, Peter, Bock, Paul E., Camire, Rodney M., Krishnaswamy, Sriram
Argitaratua 2007

Restoring the Procofactor State of Factor Va-like Variants by Complementation with B-domain Peptides

nork Bunce, Matthew W., Bos, Mettine H. A., Krishnaswamy, Sriram, Camire, Rodney M.
Argitaratua 2013

Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13

nork Cao, Wenjing, Krishnaswamy, Sriram, Camire, Rodney M., Lenting, Peter J., Zheng, X. Long
Argitaratua 2008

Interaction of factor V B-domain acidic region with its basic region and with TFPI/TFPI2: Structural insights from molecular modeling studies

nork Vadivel, Kanagasabai, Kumar, Yogesh, Bunce, Matthew W., Camire, Rodney M., Bajaj, Madhu S., Bajaj, S. Paul
Argitaratua izan da Int Biol Rev (2017)

Novel therapeutic approach for hemophilia using gene delivery of an engineered secreted activated Factor VII

nork Margaritis, Paris, Arruda, Valder R., Aljamali, Majed, Camire, Rodney M., Schlachterman, Alexander, High, Katherine A.
Argitaratua 2004

Enhancing functional platelet release in vivo from in vitro–grown megakaryocytes using small molecule inhibitors

nork Jarocha, Danuta, Vo, Karen K., Lyde, Randolph B., Hayes, Vincent, Camire, Rodney M., Poncz, Mortimer
Argitaratua izan da Blood Adv (2018)

Hyperactivity of factor IX Padua (R338L) depends on factor VIIIa cofactor activity

nork Samelson-Jones, Benjamin J., Finn, Jonathan D., George, Lindsey A., Camire, Rodney M., Arruda, Valder R.
Argitaratua izan da JCI Insight (2019)

Factor VII mutant V154G models a zymogen-like form of factor VIIa.

nork Toso, Raffaella, Bernardi, Francesco, Tidd, Theresa, Pinotti, Mirko, Camire, Rodney M, Marchetti, Giovanna, High, Katherine A, Pollak, Eleanor S
Argitaratua 2003