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Rendering Factor Xa Zymogen-like as a Therapeutic Strategy to Treat Bleeding

PURPOSE OF REVIEW: New therapies are needed to control bleeding in a range of clinical conditions. This review will discuss the biochemical properties of zymogen-like FXa, its pre-clinical assessment in different model systems, and future development prospects. RECENT FINDINGS: Underlying many proco...

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Detalhes bibliográficos
Publicado no:Curr Opin Hematol
Main Authors: Thalji, Nabil K., Camire, Rodney M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629015/
https://ncbi.nlm.nih.gov/pubmed/28692575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000369
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